15919-49-0

Upstream product

• 61285-47-0 (1,3-dimethyl-butyliden)-aniline 
• 108-11-2 Methyl isobutyl carbinol 
• 62-53-3 aniline 
• 108-10-1 4-methyl-2-pentanone 
• 67-63-0 isopropyl alcohol 

Downstream Products

• 111064-23-4 N-(1,3-dimethyl-butyl)-acetanilide 
• 944727-90-6 C₂₂H₃₉N 

Relevant academic research and scientific papers

Colloid and nanodimensional catalysts in organic synthesis: VIII. Hydrogenation of C=N bond with hydrogen in the presence of colloid nickel

Hydrogenation of azomethines with hydrogen at atmospheric pressure using nickel nanoparticles as catalyst was carried out. Reaction may be used for the preparation of secondary amines under mild conditions on an available catalyst. Continuation of studies will lead to development of a convenient method for the reductive amination of carbonyl compounds.

Efficient hydrosilylation of imines using catalysts based on iridium(iii) metallacycles

Ir(iii) metallacycles were applied as catalysts for the hydrosilylation of various ketimines and aldimines with sodium tetrakis[(3,5-trifluoromethyl)phenyl]borate, NaBArF24, as an additive. By using a slight excess of the organosilane reagent, the reactions proceeded rapidly and efficiently, at low catalyst loadings and at room temperature. Several examples of cationic Ir(iii) catalysts could be synthesised, characterized and tested. In situ-generated catalysts proved to be more active as compared to isolated ones and species with non-coordinating BArF24 counterion gave the highest catalytic activities.

One-pot reductive amination of aldehydes and ketones with α-picoline-borane in methanol, in water, and in neat conditions

A one-pot reductive amination of aldehydes and ketones with amines using α-picoline-borane as a reducing agent is described. The reaction has been carried out in MeOH, in H2O, and in neat conditions in the presence of small amounts of AcOH. This is a highly efficient and mild procedure that is applicable for a wide variety of substrates. In particular, this is the first successful demonstration that this type of reaction can be carried out in water and in neat conditions.