15923-40-7

Usage

Uses

Used in Pharmaceutical Industry:
N-Benzoyl-4-perhydroazepinone is used as an intermediate in the synthesis of pharmaceuticals for its potential role in the development of new drugs. Its unique chemical structure allows it to be a versatile building block in the creation of bioactive compounds with therapeutic benefits.
Used in Organic Chemistry:
N-Benzoyl-4-perhydroazepinone is used as a building block in organic chemistry for the preparation of various bioactive compounds. Its chemical properties make it a valuable component in the synthesis of complex organic molecules with potential applications in medicine and other fields.
Used in Medical Research:
N-Benzoyl-4-perhydroazepinone is used in medical research for its potential therapeutic benefits. Its pharmacological properties have been studied, and it has shown promise in the development of new drugs with potential applications in treating various diseases and conditions.

InChI:InChI=1/C13H15NO2/c15-12-7-4-9-14(10-8-12)13(16)11-5-2-1-3-6-11/h1-3,5-6H,4,7-10H2

Synthetic route

azepan-4-one hydrochloride (50492-22-3) + benzoyl chloride (98-88-4) → 1-benzoylazepan-4-one (15923-40-7)

Conditions	Yield
With triethylamine In dichloromethane for 16h;	76%
With triethylamine In dichloromethane at 0 - 15℃; for 3h;

diazomethane (186581-53-3, 908094-01-9) + 1-Benzoyl-4-piperidone (24686-78-0) → 1-benzoylazepan-4-one (15923-40-7)

Upstream product

• 186581-53-3 diazomethane 
• 24686-78-0 1-Benzoyl-4-piperidone 
• 188975-88-4 tert-butyl 4-oxoazepane-1-carboxylate 
• 50492-22-3 azepan-4-one hydrochloride 
• 98-88-4 benzoyl chloride 

Downstream Products

• 16803-06-8 8-benzyl-1,4-dioxa-8-aza-spiro[4.6]undecane 
• 16803-07-9 1,4-dioxan-8-azaspiro[4.6]undecane 
• 303801-73-2 (9-chloro-1,2,4,5-tetrahydroazepino[4,5-b]indol-3(6H)-yl)(phenyl)methanone 
• 1228539-16-9 6-benzoyl-3-nitro-5,7,8,9-tetrahydro-5H-pyrido[3,2-c]azepine 
• 1228539-19-2 7-benzoyl-3-nitro-5,6,8,9-tetrahydro-5H-pyrido[3,2-c]azepine 

Relevant academic research and scientific papers

CONJUGATED PROTEINS AND USES THEREOF

Disclosed herein, in certain embodiments, are protein-probe adducts and synthetic ligands that inhibit protein-probe adduct formation, in which the proteins are regulated by NRF2. In some instances, also described herein are protein-binding domains that interact with a probe and/or a ligand described herein, in which the proteins are regulated by NRF2.

1,3,4,9-TETRAHYDRO-2H-PYRIDO[3,4-B]INDOLE DERIVATIVE COMPOUNDS AND USES THEREOF

The present invention relates to 1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indole derivative compounds and uses thereof. In particular, compounds of the invention have antibacterial activity and/or are capable of re-sensitizing methicillin-resistant Staphylococcus aureus to a P-lactam antibiotic or a combination of a P-lactam antibiotic and a P-lactamase inhibitor. The present invention also relates to a method for producing and using said compounds.