16803-07-9

Usage

Chemical structure

A spirocyclic compound with two oxygen atoms and one nitrogen atom.

Application

Used in the synthesis of pharmaceuticals and other organic compounds, particularly in the production of heterocyclic compounds.

Biological activities

Known for its potential anti-cancer and anti-inflammatory properties.

Research focus

Being studied for its potential use in drug development.

Structural significance

Its spirocyclic nature makes it a valuable building block in the synthesis of complex organic molecules.

Role in organic chemistry

Plays an important role in the field of organic chemistry and drug discovery.

Upstream product

• 15923-40-7 1-benzoylazepan-4-one 
• 37637-20-0 2-Aza-1,5-cycloheptanedione 
• 107-21-1 ethylene glycol 
• 346735-03-3 ethyl 1,4-dioxa-8-azaspiro[4.6]undecane-8-carboxylate 
• 16803-06-8 8-benzyl-1,4-dioxa-8-aza-spiro[4.6]undecane 

Downstream Products

• 346735-04-4 8-[2-(4-methoxyphenyl)ethyl]-1,4-dioxa-8-azaspiro[4.6]undecane 
• 19869-42-2 1-methyl-1,2,3,5,6,7-hexahydroazepin-4-one hydrochloride 

Relevant academic research and scientific papers

Method for preparing N-methyl azepine-4-one hydrochloride

The invention discloses a method for preparing N-methyl azepine-4-one hydrochloride. According to the method, 4-oxime cyclohexanone is taken as a raw material, aza-cycloheptane-2,5-diketone is obtained under a Beckmann rearrangement condition, aza-cycloheptane-2,5-diketone and ethylene glycol are subjected to condensation to generate ketal, amide is reduced through red aluminum, methylation is performed, ethylene glycol is removed under a hydrochloric acid condition, and finally N-methyl azepine-4-one hydrochloride is obtained. The invention provides a safe, reliable and efficient synthetic route, the raw materials are low in price, the reaction conditions are mild, explosive diazomethane does not need to be used, methyl acrylate which is easy to polymerize and high in carcinogenesis is also not needed, and the method is more suitable for large-scale industrial production.

Substituted homopiperidinyl benzimidazole analogues as fundic relaxants

The present invention relates to compounds of formula (I) their prodrugs, N-oxides, addition salts, quaternary amines and stereochemically isomeric forms, wherein the bivalent radical —{circle over (A)}— represents a saturated or an unsaturated homopiperi