15926-45-1

Upstream product

• 825-60-5 benzimidic acid ethyl ester 
• 459-73-4 GlyOEt*HCl 
• 623-33-6 glycine ethyl ester hydrochloride 

Downstream Products

• 106013-34-7 5,5-Dibenzyl-2-phenyl-4,5-dihydro-oxazole 
• 106013-42-7 5,5-Bis-(2-methyl-allyl)-2-phenyl-4,5-dihydro-oxazole 
• 106013-40-5 5,5-Diallyl-2-phenyl-4,5-dihydro-oxazole 
• 106013-33-6 5,5-Diethyl-2-phenyl-4,5-dihydro-oxazole 
• 36746-50-6 2,5,5-triphenyl-4,5-dihydrooxazole 
• 33561-48-7 5,5-dimethyl-2-phenyl-4,5-dihydrooxazole 
• 15926-46-2 diethyl 2-phenyl-4,5-oxazoledicarboxylate 
• 92126-37-9 2-phenyl-4,5-bis(hydroxymethyl)oxazole bis(methylcarbamate) 
• 92126-36-8 (4-Hydroxymethyl-2-phenyl-oxazol-5-yl)-methanol 

Relevant academic research and scientific papers

Synthesis and evaluation of furan, thiophene, and azole bis[(carbamoyloxy)methyl] derivatives as potential antineoplastic agents

A series of bis(hydroxymethyl)-substituted heterocycles were synthesized and converted to the corresponding bis(methylcarbamate) derivatives. The heterocyclic systems studied were based on 2-phenyl-3-methylfuran, 1-phenylpyrazole, 1-phenyl-5-methylpyrazole, 1-phenyl-5-methylthiopene, 1-phenyl-1,2,3-triazole, 3-phenylisoxazole, 3-phenylisothiazole, 2-phenylthiazole, and 2-phenyloxazole. None of the bis(carbamates) prepared was active against murine P388 lymphocytic leukemia. Pyrrole bis(carbamate), which exhibited antileukemic activity, also showed reactivity toward 4-(p-nitrobenzyl)pyridine while the inactive bis(carbamates) were unreactive in the 4-(p-nitrobenzyl)pyridine assay.