15929-43-8

Usage

Uses

Used in Coating Materials Industry:
Bis(4-(trifluoromethyl)phenyl)phosphine oxide is used as a photoinitiator for the curing of coating materials. Its ability to efficiently initiate photochemical reactions allows for faster and more effective curing processes, improving the performance and durability of the coatings.
Used in Adhesives Industry:
In the adhesives industry, bis(4-(trifluoromethyl)phenyl)phosphine oxide serves as a photoinitiator for the curing of adhesives. This enables a faster curing process, resulting in stronger and more durable bonds between materials.
Used in Inks Industry:
Bis(4-(trifluoromethyl)phenyl)phosphine oxide is used as a photoinitiator in the curing of inks. Its high thermal stability and ability to initiate photochemical reactions contribute to the production of high-quality inks with improved performance and durability.
Used in Polymer Manufacturing:
Bis(4-(trifluoromethyl)phenyl)phosphine oxide is utilized in the manufacturing of polymers. Its properties make it a valuable component in the production of various types of polymers with specific characteristics and applications.
Used as a Stabilizer in Plastics Industry:
In the plastics industry, bis(4-(trifluoromethyl)phenyl)phosphine oxide is used as a stabilizer. Its high thermal stability helps to prevent the degradation of plastics, ensuring their longevity and maintaining their properties over time.
It is important to handle bis(4-(trifluoromethyl)phenyl)phosphine oxide with caution and proper safety measures, as it can be hazardous if not used properly.

Upstream product

• 13685-91-1 (diethylamino)bis(4-trifluoromethylphenyl)phosphane 
• 13406-27-4 tris(4-trifluoromethylphenyl)phosphine oxide 
• 402-43-7 p-trifluoromethylphenyl bromide 
• 402-51-7 4-(trifluoromethyl)phenylmagnesium bromide 
• 762-04-9 phosphonic acid diethyl ester 
• 13685-24-0 bis(4-trifluoromethylphenyl)phosphine chloride 
• 762-04-9 Diethyl phosphonate 

Downstream Products

• 15929-46-1 Bis-(p-trifluormethyl-phenyl)-thiolphosphinsaeure-phenylester 
• 13685-24-0 bis(4-trifluoromethylphenyl)phosphine chloride 
• 282536-67-8 (R)-(+)-2-(bis(4-trifluoromethylphenyl)phosphinyl)-2'-methoxy-1,1'-binaphthyl 
• 98507-89-2 (PrCl₃((CF₃C₆H₄)2PHO)3) 
• 98507-95-0 (DyCl₃((CF₃C₆H₄)2PHO)3) 
• 99665-68-6 potassium bis(4-(trifluoromethyl)phenyl)phosphide 
• 1255859-74-5 (S)-2-(2-(bis(4-trifluoromethyl-phenyl)phosphoryl))-5-(4-trifluoromethyl-phenyl)-4-tert-butyl-4,5-dihydro-oxazole 
• 1255859-78-9 C₃₉H₃₂F₆NO₂P 
• 1372559-65-3 phenylbis(4-(trifluoromethyl)phenyl)phosphine oxide 

Relevant academic research and scientific papers

B(C6F5)3-catalyzed O-H insertion reactions of diazoalkanes with phosphinic acids

A highly efficient base-, metal-, and oxidant-free catalytic O-H insertion reaction of diazoalkanes and phosphinic acids in the presence of B(C6F5)3has been developed. This powerful methodology provides a green approach towards the synthesis of a broad spectrum of α-phosphoryloxy carbonyl compounds with good to excellent yields (up to 99% yield). The protocol features the advantages of operational simplicity, high atom economy, practicality, easy scalability and environmental friendliness.

The organocatalytic enantiodivergent fluorination of β-ketodiaryl-phosphine oxides for the construction of carbon-fluorine quaternary stereocenters

Commercially available cinchona alkaloids that can catalyze the enantiodivergent fluorination of β-ketodiarylphosphine oxides were developed to construct carbon-fluorine quaternary stereocenters. This protocol features a wide scope of substrates and excellent enantioselectivities, and it is scalable.

Twofold C?H Activation-Based Enantio- and Diastereoselective C?H Arylation Using Diarylacetylenes as Rare Arylating Reagents

C?H bond activation has been established as an attractive strategy to access axially chiral biaryls, and the most straightforward method is direct C?H arylation of arenes. However, the arylating source has been limited to several classes of reactive and bulky reagents. Reported herein is rhodium-catalyzed 1:2 coupling of diarylphosphinic amides and diarylacetylenes for enantio- and diastereoselective construction of biaryls with both central and axial chirality. This twofold C?H activation reaction stays contrast to the previously explored Miura–Satoh type 1:2 coupling of arenes and alkynes in terms of chemoselectivity and proceeded under mild conditions with the alkyne acting as a rare arylating reagent. Both C?H activation events are stereo-determining and are under catalyst control, with the 2nd C?H activation being diastereo-determining in a remote fashion. Analysis of the stereochemistry of the major and side products suggests moderate enantioselectivity of the initial C?H activation–desymmetrization process. However, the minor (R) rhodium vinyl intermediate is consumed more readily in undesired protonolysis, eventually resulting in high enantio- and diastereoselectivity of the major product.

Electrochemical Dehydrogenative Phosphorylation of Alcohols for the Synthesis of Organophosphinates

An eco-friendly and efficient method for the synthesis of organophosphinates via an electrochemical cross-dehydrogenative-coupling reaction between alcohols and secondary phosphine oxides has been developed. This electrochemical reaction was conducted at

Highly chemo- and regioselective C-P cross-coupling reaction of quinone imine ketals with Ar2P(O)H to construct: Ortho -amino triarylphosphine derivatives

A highly chemo- and regioselective approach for the construction of ortho-amino triarylphosphine oxides has been achieved through a C-P cross-coupling reaction involving quinone imine ketals (QIKs) with Ar2P(O)H and catalyzed via a Lewis base. This alternative protocol provided a wide substrate scope with excellent yields (82-95%), and a variety of ortho-amino triarylphosphines were obtained with high yields (87-95%) via further reductive reaction. Furthermore, this reaction could be scaled-up and several synthetic transformations were accomplished for the construction of functionalized organophosphorus.

Rhodium catalyzed C-C bond cleavage/coupling of 2-(azetidin-3-ylidene)acetates and analogs

The C-C bond cleavage/coupling of 2-(azetidin-3-ylidene)acetates with aryl boronic acids catalyzed by a rhodium complex was studied with a "conjugate addition/β-C cleavage/protonation" strategy.

Copper-catalyzed C–P cross-coupling of secondary phosphines with (hetero)aromatic bromide

A novel and convenient approach to the synthesis of various tertiary phosphines via a copper-catalyzed cross-coupling of (hetero)aromatic bromide with secondary phosphines has been developed. The reaction employs cheap copper as the catalyst, 2,6-bis(N-methylaminomethyl)pyridine (L4) as a perfect ligand and KOtBu as a base; all reactions are carried out under argon atmosphere. A variety of sterically hindered and/or functionalized substrates were found to react under these reaction conditions to provide products in good to excellent yields. Moreover, ten new tertiary phosphines were first reported in this process.

Dearylation of arylphosphine oxides using a sodium hydride-iodide composite

A new protocol for the dearylation of arylphosphine oxides was developed using sodium hydride (NaH) in the presence of lithium iodide (LiI). The transient sodium phosphinite could be functionalized with a range of electrophiles in a one-pot fashion.

Outer-Sphere Reactivity Shift of Secondary Phosphine Oxide-Based Nickel Complexes: From Ethylene Hydrophosphinylation to Oligomerization

A new dimension for secondary phosphine oxide (SPOs) ligands is described in this article. Demonstrated on original π-allylic nickel structures, these self-assembled complexes trigger catalytic hydrophosphinylation reactions. Addition of a Lewis acid B(C6F5)3 switches the reactivity towards migratory insertion and thus ethylene oligomerization through an unprecedented outer-sphere interaction with the coordinated SPO ligand. NMR experiments and X-ray analyses allowed for the observation of the formation of zwitterionic active species as well as their degradation pathway.

Rapid synthesis of an electron-deficient t-BuPHOX ligand: Cross-coupling of aryl bromides with secondary phosphine oxides

Herein an efficient and direct copper-catalyzed coupling of oxazoline-containing aryl bromides with electron-deficient secondary phosphine oxides is reported. The resulting tertiary phosphine oxides can be reduced to prepare a range of PHOX ligands. The p