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159303-54-5

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  • METHYL (3S,6S,8AS)-6-[(TERT-BUTOXYCARBONYL)AMINO]-5-OXOOCTAHYDROINDOLIZINE-3-CARBOXYLATE

    Cas No: 159303-54-5

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159303-54-5 Usage

General Description

METHYL (3S,6S,8AS)-6-[(TERT-BUTOXYCARBONYL)AMINO]-5-OXOOCTAHYDROINDOLIZINE-3-CARBOXYLATE is a chemical compound with a complex structure consisting of a methyl ester group attached to a carboxylic acid group, as well as a tert-butoxycarbonyl amino group. The compound also contains a five-membered ring with a ketone group, as well as a six-membered ring with a nitrogen atom. METHYL (3S,6S,8AS)-6-[(TERT-BUTOXYCARBONYL)AMINO]-5-OXOOCTAHYDROINDOLIZINE-3-CARBOXYLATE may have potential applications in organic synthesis, pharmaceuticals, or biochemistry, but further research and testing would be necessary to determine its specific uses and properties in practical applications.

Check Digit Verification of cas no

The CAS Registry Mumber 159303-54-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,9,3,0 and 3 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 159303-54:
(8*1)+(7*5)+(6*9)+(5*3)+(4*0)+(3*3)+(2*5)+(1*4)=135
135 % 10 = 5
So 159303-54-5 is a valid CAS Registry Number.

159303-54-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name METHYL (3S,6S,8AS)-6-[(TERT-BUTOXYCARBONYL)AMINO]-5-OXOOCTAHYDROINDOLIZINE-3-CARBOXYLATE

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:159303-54-5 SDS

159303-54-5Relevant articles and documents

Synthesis of Conformationally Constrained Dipeptide Mimetics with Azabicyclo[4,3,0]nonanone and Azabicyclo[5,3,0]decanone Scaffolds

Xi, Wanlin,Du, Lei,Zhang, Liping,Sun, Haiying

, p. 10182 - 10188 (2020)

A general and efficient method for the synthesis of azabicyclo[4,3,0]nonanone and azabicyclo[5,3,0]decanone amino acid derivatives was developed with the palladium-catalyzed coupling of intermediates 9 and 10 with BocNH2 and Boc2NH and the following reduction of the C-C double bond by hydrogenation as the key steps. The exploration of the synthesis of C6-substituted dipeptide mimetics from 9 and 10 using Suzuki coupling as the key reaction has also been performed.

Paired Utility of Aza-Amino Acyl Proline and Indolizidinone Amino Acid Residues for Peptide Mimicry: Conception of Prostaglandin F2α Receptor Allosteric Modulators That Delay Preterm Birth

Mir, Fatemeh M.,Atmuri, N. D. Prasad,Bourguet, Carine B.,Fores, Jennifer Rodon,Hou, Xin,Chemtob, Sylvain,Lubell, William D.

, p. 4500 - 4525 (2019/05/17)

Peptide mimicry employing a combination of aza-amino acyl proline and indolizidinone residues has been used to develop allosteric modulators of the prostaglandin F2α receptor. The systematic study of the N-terminal phenylacetyl moiety and the conformation and side chain functions of the central turn dipeptide residue has demonstrated the sensitive relationships between modulator activity and topology. Examination of aza-Gly-Pro and aza-Phe-Pro analogs 2a and 2b in a murine preterm labor model featuring treatment with lipopolysaccharide demonstrated their capacity to extend significantly (>20 h) the average time of delivery offering new prototypes for delaying premature birth.

Anodic amide oxidation/olefin metathesis strategies: Developing a unified approach to the synthesis of bicyclic lactam peptidomimetics

Beal, Laura M,Liu, Bin,Chu, Wenhua,Moeller, Kevin D

, p. 10113 - 10125 (2007/10/03)

In connection with efforts to build constrained peptidomimetics for the endocrine hormone TRH, a general strategy for the construction of bicyclic lactam peptide building blocks has been developed. This strategy used an anodic amide oxidation to selective

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