756820-38-9

Basic information

• Product Name: ((3S,6S,8aS)-3-Benzylcarbamoyl-5-oxo-octahydro-indolizin-6-yl)-carbamic acid tert-butyl ester
• Synonyms: ((3S,6S,8aS)-3-Benzylcarbamoyl-5-oxo-octahydro-indolizin-6-yl)-carbamic acid tert-butyl ester
• CAS NO: 756820-38-9
• Molecular Weight: 387.479
• Mol File: 756820-38-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ((3S,6S,8aS)-3-Benzylcarbamoyl-5-oxo-octahydro-indolizin-6-yl)-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: ((3S,6S,8aS)-3-Benzylcarbamoyl-5-oxo-octahydro-indolizin-6-yl)-carbamic acid tert-butyl ester(756820-38-9)
• EPA Substance Registry System: ((3S,6S,8aS)-3-Benzylcarbamoyl-5-oxo-octahydro-indolizin-6-yl)-carbamic acid tert-butyl ester(756820-38-9)

Safety Data

• Hazardous Substances Data: 756820-38-9(Hazardous Substances Data)

Upstream product

• 159303-50-1 (3S,6S,9S)-2-oxo-3--1-azabicyclo<4.3.0>nonane-9-carboxylic acid 
• 100-46-9 benzylamine 
• 159303-54-5 (3S,6S,9S)-methyl 2-oxo-3--1-azabicyclo<4.3.0>nonane-9-carboxylate 

Downstream Products

• 756820-36-7 [(S)-1-((3S,6S,8aS)-3-Benzylcarbamoyl-5-oxo-octahydro-indolizin-6-ylcarbamoyl)-ethyl]-carbamic acid tert-butyl ester 

Relevant articles and documents

Structure-based design, synthesis, and evaluation of conformationally constrained mimetics of the second mitochondria-derived activator of caspase that target the X-linked inhibitor of apoptosis protein/caspase-9 interaction site

A successful structure-based design of conformationally constrained second mitochondria-derived activator of caspase (Smac) mimetics that target the XIAP/caspase-9 interaction site is described. The most potent Smac mimetic 12d has a Ki of 350