159496-16-9

Basic information

• Product Name: [1',2',3',4',5''-13C5]URIDINE
• Synonyms: [1',2',3',4',5''-13C5]URIDINE;RHWBWGWJEKFADU-XQLHBIPJSA-N
• CAS NO: 159496-16-9
• Molecular Formula: C9H12N2O6
• Molecular Weight: 249.25
• Mol File: 159496-16-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: [1',2',3',4',5''-13C5]URIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: [1',2',3',4',5''-13C5]URIDINE(159496-16-9)
• EPA Substance Registry System: [1',2',3',4',5''-13C5]URIDINE(159496-16-9)

Safety Data

• Hazardous Substances Data: 159496-16-9(Hazardous Substances Data)

Usage

Uses

Labelled Uridine, a nucleoside; widely distributed in nature. Uridine is one of the four basic components of ribonucleic acid (RNA)

Upstream product

• 66-22-8 uracil 
• 159496-09-0 [13C5]-1,2-di-O-acetyl-3,5-di-O-benzoyl-α,β-D-ribofuranose 
• 238096-59-8 <1',2',3',4',5'-13C5>-2',3',5'-tri-O-(4-toluoyl)-uridine 
• 159496-08-9 C₄⁽¹³⁾C₅H₁₆O₇S 

Downstream Products

• 238096-68-9 C₃₁⁽¹³⁾C₅H₄₄N₂O₈Si 
• 389143-50-4 5'-O-(4,4'-dimethoxytrityl)-2'-O-t-butyldimethylsilyl-[(1',2',3',4',5'-13C₅)-(5-2H)]-uridine 
• 389143-46-8 5'-O-(4,4'-dimethoxytrityl)-[(1',2',3',4',5'-13C₅)-(5-2H)]-uridine 
• 389143-41-3 2',3',5'-tri-O-acetyl-O⁴-(2-nitrophenyl)-[(1',2',3',4',5'-13C₅)-(5-2H)]-uridine 
• 238096-65-6 C₂₅⁽¹³⁾C₅H₃₀N₂O₈ 

Relevant articles and documents

Synthesis of multiply labelled ribonucleosides for sequence-specific labelling of oligo-RNA

The synthesis of ribonucleotide blocks multiply labelled with 2H, 13C and 15N for solid support synthesis of sequence specifically labelled RNA is described. Labels were introduced in the ribose ring (13C), C5 position of pyrimidine nucleobases (2H) and exocyclic amino groups (15N) and serve as multiple probes for studying the various physicochemical consequences of physiologically important RNA folding by high-resolution multi-nuclear NMR spectroscopy.

Chemical Synthesis of 13C-labelled Monomers for the Solid-Phase and Template Controlled Enzymatic Synthesis of DNA and RNA Oligomers

The preparation of 13C-labelled ribonucleosides starting from -glucose 1 and the corresponding nucleobases 5a-e or 6a-e (N6-benzoyl-adenine, N2-acetyl-guanine, N4-benzoyl-cytosine, uracil and thymine) in 47-66percent overall yield is described.Their subsequent transformation into 5'-O-dimethoxytrityl protected DNA-phosphoramidites and 5'-O-dimethoxytrityl-2'-O-trialkylsilyl protected RNA-phosphor-amidites for the solid phase synthesis of DNA- and RNA-oligomers and to 5'-O-ribo- and deoxyribo-nucleosidetriphosphates for template controlled enzymatic synthesis (polymerase- or reverse transcriptase reaction) has been carried out.