159503-24-9

Basic information

• Product Name: 4'-AMINO-BIPHENYL-3-CARBOXYLIC ACID METHYL ESTER
• Synonyms: SALOR-INT L480207-1EA;SALOR-INT L480592-1EA;AKOS BAR-0134;AKOS BAR-0153;3'-AMINOBIPHENYL-4-CARBOXYLIC ACID METHYL ESTER;4'-AMINO-BIPHENYL-3-CARBOXYLIC ACID METHYL ESTER;METHYL 3'-AMINO[1,1'-BIPHENYL]-4-CARBOXYLATE;METHYL 4'-AMINO[1,1'-BIPHENYL]-3-CARBOXYLATE
• CAS NO: 159503-24-9
• Molecular Formula: C₁₄H₁₃NO₂
• Molecular Weight: 227.26
• Mol File: 159503-24-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 411.779 °C at 760 mmHg
• Flash Point: 242.097 °C
• Appearance: /
• Density: 1.166 g/cm³
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 4.05±0.10(Predicted)
• CAS DataBase Reference: 4'-AMINO-BIPHENYL-3-CARBOXYLIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-AMINO-BIPHENYL-3-CARBOXYLIC ACID METHYL ESTER(159503-24-9)
• EPA Substance Registry System: 4'-AMINO-BIPHENYL-3-CARBOXYLIC ACID METHYL ESTER(159503-24-9)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 159503-24-9(Hazardous Substances Data)

Usage

Description

4'-Amino-biphenyl-3-carboxylic acid methyl ester, with the molecular formula C14H13NO2, is a methyl ester derivative of 4'-amino-biphenyl-3-carboxylic acid. This chemical compound serves as an intermediate in the synthesis of pharmaceuticals and other organic compounds, known for its improved stability and solubility, making it a valuable asset in both industrial and research applications.

Uses

Used in Pharmaceutical Industry:
4'-Amino-biphenyl-3-carboxylic acid methyl ester is used as a key intermediate in the synthesis of various drugs and medicine formulations, contributing to the development of novel therapeutic agents.
Used in Scientific Research:
As a research chemical, 4'-Amino-biphenyl-3-carboxylic acid methyl ester is utilized in scientific studies and experiments, aiding in the exploration of new chemical reactions and the advancement of organic chemistry.

Upstream product

• 5798-75-4 Ethyl 4-bromobenzoate 
• 591-19-5 m-Bromoaniline 
• 13331-27-6 m-nitrobenzene boronic acid 
• 89900-93-6 3'-nitro-[1,1'-biphenyl]-4-carboxylic acid methyl ester 
• 619-42-1 4-methoxycarbonylphenyl bromide 

Relevant articles and documents

Synthesis and biological evaluation of a novel photo-activated histone deacetylase inhibitor

Hydroxamic acid-based histone deacetylase inhibitors (HDACi) are a class of epigenetic agents with potentially broad therapeutic application to several disease states including post angioplasty mediated neointimal hyperplasia (NIH). Precise spatiotemporal

Biarylaniline phenethanolamines as potent and selective β3 adrenergic receptor agonists

The synthesis of a series of phenethanolamine aniline agonists that contain an aniline ring on the right-hand side of the molecule substituted at the meta position with a benzoic acid or a pyridyl carboxylate is described. Several of the analogues (e.g.,

Palladium-catalyzed coupling of functionalized bromoarenes to a polystyrene-bound aryl tributylstannane

The Stille reaction with a polystyrene-bound stannyl component, catalyzed by a palladacycle complex, provides a convenient and clean method for the synthesis of substituted biaryls on the resin. Several functional groups useful for the construction of supported polydentate amino alcohols were successfully introduced.