159503-24-9

Basic information

• Product Name: 4'-AMINO-BIPHENYL-3-CARBOXYLIC ACID METHYL ESTER
• Synonyms: SALOR-INT L480207-1EA;SALOR-INT L480592-1EA;AKOS BAR-0134;AKOS BAR-0153;3'-AMINOBIPHENYL-4-CARBOXYLIC ACID METHYL ESTER;4'-AMINO-BIPHENYL-3-CARBOXYLIC ACID METHYL ESTER;METHYL 3'-AMINO[1,1'-BIPHENYL]-4-CARBOXYLATE;METHYL 4'-AMINO[1,1'-BIPHENYL]-3-CARBOXYLATE
• CAS NO: 159503-24-9
• Molecular Formula: C₁₄H₁₃NO₂
• Molecular Weight: 227.26
• Mol File: 159503-24-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 411.779 °C at 760 mmHg
• Flash Point: 242.097 °C
• Appearance: /
• Density: 1.166 g/cm³
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 4.05±0.10(Predicted)
• CAS DataBase Reference: 4'-AMINO-BIPHENYL-3-CARBOXYLIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-AMINO-BIPHENYL-3-CARBOXYLIC ACID METHYL ESTER(159503-24-9)
• EPA Substance Registry System: 4'-AMINO-BIPHENYL-3-CARBOXYLIC ACID METHYL ESTER(159503-24-9)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 159503-24-9(Hazardous Substances Data)

Usage

Description

4'-Amino-biphenyl-3-carboxylic acid methyl ester, with the molecular formula C14H13NO2, is a methyl ester derivative of 4'-amino-biphenyl-3-carboxylic acid. This chemical compound serves as an intermediate in the synthesis of pharmaceuticals and other organic compounds, known for its improved stability and solubility, making it a valuable asset in both industrial and research applications.

Uses

Used in Pharmaceutical Industry:
4'-Amino-biphenyl-3-carboxylic acid methyl ester is used as a key intermediate in the synthesis of various drugs and medicine formulations, contributing to the development of novel therapeutic agents.
Used in Scientific Research:
As a research chemical, 4'-Amino-biphenyl-3-carboxylic acid methyl ester is utilized in scientific studies and experiments, aiding in the exploration of new chemical reactions and the advancement of organic chemistry.

Upstream product

• 5798-75-4 Ethyl 4-bromobenzoate 
• 619-42-1 4-methoxycarbonylphenyl bromide 
• 13331-27-6 m-nitrobenzene boronic acid 
• 89900-93-6 3'-nitro-[1,1'-biphenyl]-4-carboxylic acid methyl ester 
• 591-19-5 m-Bromoaniline 

Relevant articles and documents

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Biarylaniline phenethanolamines as potent and selective β3 adrenergic receptor agonists

The synthesis of a series of phenethanolamine aniline agonists that contain an aniline ring on the right-hand side of the molecule substituted at the meta position with a benzoic acid or a pyridyl carboxylate is described. Several of the analogues (e.g.,

Palladium-catalyzed coupling of functionalized bromoarenes to a polystyrene-bound aryl tributylstannane

The Stille reaction with a polystyrene-bound stannyl component, catalyzed by a palladacycle complex, provides a convenient and clean method for the synthesis of substituted biaryls on the resin. Several functional groups useful for the construction of supported polydentate amino alcohols were successfully introduced.