159503-24-9Relevant articles and documents
Synthesis and biological evaluation of a novel photo-activated histone deacetylase inhibitor
Dear, Anthony E.,Liu, Hongbin,Mountford, Simon,Robinson, Andrea,Sama, Gopal R.,Thompson, Phillip
, (2020/06/05)
Hydroxamic acid-based histone deacetylase inhibitors (HDACi) are a class of epigenetic agents with potentially broad therapeutic application to several disease states including post angioplasty mediated neointimal hyperplasia (NIH). Precise spatiotemporal
Biarylaniline phenethanolamines as potent and selective β3 adrenergic receptor agonists
Uehling, David E.,Shearer, Barry G.,Donaldson, Kelly H.,Chao, Esther Y.,Deaton, David N.,Adkison, Kim K.,Brown, Kathleen K.,Cariello, Neal F.,Faison, Walter L.,Lancaster, Mary E.,Lin, Jasmine,Hart, Robert,Milliken, Tula O.,Paulik, Mark A.,Sherman, Bryan W.,Sugg, Elizabeth E.,Cowan, Conrad
, p. 2758 - 2771 (2007/10/03)
The synthesis of a series of phenethanolamine aniline agonists that contain an aniline ring on the right-hand side of the molecule substituted at the meta position with a benzoic acid or a pyridyl carboxylate is described. Several of the analogues (e.g.,
Palladium-catalyzed coupling of functionalized bromoarenes to a polystyrene-bound aryl tributylstannane
Brody, Marcus S.,Finn
, p. 415 - 418 (2007/10/03)
The Stille reaction with a polystyrene-bound stannyl component, catalyzed by a palladacycle complex, provides a convenient and clean method for the synthesis of substituted biaryls on the resin. Several functional groups useful for the construction of supported polydentate amino alcohols were successfully introduced.