159581-77-8Relevant academic research and scientific papers
Incorporation of an amino function in a (1S,2S,3R)-3-hydroxy-2-methoxy-1- cyclohexane carboxylic acid
Mayer,Joullie
, p. 2351 - 2365 (1994)
(1S,2S,3R)-3-Hydroxy-2-methoxy-1-cyclohexanecarboxylic acid was synthesized for the construction of an amino acid to be used in a constrained ring didemnin B analog (2). The amine functionality was introduced into the cyclohexane ring by reductive amination using sodium triacetoxyborohydride or by oxime formation followed by reduction.
