Incorporation of an amino function in a (1S,2S,3R)-3-hydroxy-2-methoxy-1- cyclohexane carboxylic acid

Article abstract of DOI:10.1080/00397919408019060

(1S,2S,3R)-3-Hydroxy-2-methoxy-1-cyclohexanecarboxylic acid was synthesized for the construction of an amino acid to be used in a constrained ring didemnin B analog (2). The amine functionality was introduced into the cyclohexane ring by reductive amination using sodium triacetoxyborohydride or by oxime formation followed by reduction.

Full text of DOI:10.1080/00397919408019060

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Synthetic Communications: An
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Incorporation of an Amino
Function in a (1S,2S,3R)-3-
Hydroxy-2-methoxy-1-
cyclohexane Carboxylic Acid
Scott C. Mayer a & Madeleine M. Joullié a
a Department of Chemistry , University of
Pennsylvania , Philadelphia, Pennsylvania,
19104-6323
Published online: 23 Sep 2006.
To cite this article: Scott C. Mayer & Madeleine M. Joullié (1994) Incorporation of
an Amino Function in a (1S,2S,3R)-3-Hydroxy-2-methoxy-1-cyclohexane Carboxylic
Acid, Synthetic Communications: An International Journal for Rapid Communication of
Synthetic Organic Chemistry, 24:16, 2351-2365, DOI: 10.1080/00397919408019060
To link to this article: http://dx.doi.org/10.1080/00397919408019060
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