159685-66-2

Upstream product

• 141404-08-2 (3R,5R)-3,5-bis[tert-butyl(dimethyl)silyloxy]-4-hydroxycyclohexanone 
• 2916-76-9 methyl (trimethylsilyl)acetate 
• 141404-09-3 (3R,5R)-3,5-bis<(tert-butyldimethylsilyl)oxy>-4-<(trimethylsilyl)oxy>cyclohexanone 

Downstream Products

• 159685-67-3 2-<(aR^*,3'R,5'R)-3',5'-bis<(tert-butyldimethylsilyl)oxy>-4'-<(trimethylsilyl)oxy>cyclohexylidene>ethanol 
• 159685-67-3 2-<(aS^*,3'R,5'R)-3',5'-bis<(tert-butyldimethylsilyl)oxy>-4'-<(trimethylsilyl)oxy>cyclohexylidene>ethanol 
• 160399-72-4 <(aS^*,3'R,5'R)-3',5'-bis<(tert-butyldimethylsilyl)oxy>-4'-hydroxycyclohexylidene>acetic acid methyl ester 
• 160399-72-4 <(aR^*,3'R,5'R)-3',5'-bis<(tert-butyldimethylsilyl)oxy>-4'-hydroxycyclohexylidene>acetic acid methyl ester 

Relevant academic research and scientific papers

Synthesis and biological activity of 2-hydroxy and 2-alkoxy analogs of 1α,25-dihydroxy-19-norvitamin D3

1α,2α,25-Trihydroxy-19-norvitamin D3, 1α,2β,25-trihydroxy-19- norvitamin D3, and their alkoxy analogs were efficiently prepared in a convergent synthesis, starting with (-)-quinic acid and a Windaus-Grundmann type ketone. Configurati

Synthesis of a-ring synthon of 19-nor-1alpha,25-dihydroxyvitamin D3 from (D)-glucose

The present invention provides a method for the synthesis of an A-ring synthon phosphine oxide used in the preparation of 19-nor vitamin D compounds, and to novel synthetic intermediates formed during the synthesis. The new method prepares the phosphine oxide from (D)-glucose.