159799-39-0

Upstream product

• 98-88-4 benzoyl chloride 
• 99070-42-5 3-(4-chlorophenyl)-1,4,5,6-tetrahydropyridazine 
• 74-85-1 ethene 
• 1373121-44-8 N′-(2-chloro-1-(4-chlorophenyl)ethylidene)benzohydrazide 
• 289-80-5 1,2-diazine 
• 3984-34-7 4-(4-chlorophenyl)-4-oxobutanoic acid 
• 1079-73-8 6-(4-chlorophenyl)-4,5-dihydro-3(2H)-pyridazinone 

Relevant academic research and scientific papers

Cycloaddition of in situ generated 1,2-diaza-1,3-dienes with simple olefins: Facile approaches to tetrahydropyridazines

A catalyst-free [4 + 2] annulation process between in situ generated 1,2-diaza-1,3-butadienes and simple olefins has been developed. Under mild conditions, the reactions afforded 1,4,5,6-tetrahydropyridazines, which feature a wide range of bioactive compounds, with high yields (up to 99% yield).

1-arylsulphonyl, arylcarbonyl and 1-arylphosphonyl-3-phenyl-1,4,5,6-tetrahydropyridazines

Disclosed are progestin agonists having the following formula: STR1 W is absent or --CH=CH--; R1 are independently selected from the group consisting of halogen, --CF3, and NO2, or both R1 may be joined to form a bi-radical which is --CH=CHCH=CH--; R3 are independently selected from the group consisting of hydrogen, C1-6 branched or linear alkyl, halogen and --CF3, with the proviso that R3 at the 3-position must be H where R3 at the 4-position is H, or both R3 may be joined to form a bi-radical selected from the group consisting of --CH=CHCH=CH--, --C(NC1-4 alkyl2)=CHCH=CH-- and --(CH2)4 --; R5 is selected from the group consisting of H and Me; with the proviso that only one of R1 and R3 forms the fused bi-radical; and the stereoisomers.