159885-79-7

Upstream product

• 2003-10-3 2-bromo-1-[3-(trifluoromethyl)phenyl]ethanone 
• 349-76-8 3'-(trifluoromethyl)acetophenone 
• 1048670-08-1 2-[1-ethoxy-meth-(Z)-ylidene]-4,4,4-trifluoro-3-oxo-butyric acid ethyl ester 
• 159885-58-2 4-carboetoxy-5-(trifluoromethyl)pyrazole-1-thioamide 
• 159885-60-6 2-<4-carboethoxy-5-(trifluoromethyl)pyrazol-1-yl>-4-<3-(trifluoromethyl)phenyl>thiazole 

Downstream Products

• 1025873-47-5 5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-thiazol-2-yl]-1H-pyrazole-4-carboxylic acid (3-azido-propyl)-amide 
• 1026655-81-1 5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-thiazol-2-yl]-1H-pyrazole-4-carboxylic acid (3-cyano-propyl)-amide 
• 1026813-13-7 5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-thiazol-2-yl]-1H-pyrazole-4-carboxylic acid (4-imino-butyl)-amide 
• 159886-35-8 2-[4-(3-Bromopropylcarbamoyl)-5-(trifluoromethyl)pyrazol-1-yl]-4-(3-trifluoromethylphenyl)thiazole 

Relevant academic research and scientific papers

Novel thiazole-based heterocycles as selective inhibitors of fibrinogen- mediated platelet aggregation

The synthesis and biological activity of novel thiazole-based heterocycles as inhibitors of thrombin-induced human platelet aggregation are described. Further evaluation of selected compounds show they inhibit platelet aggregation as stimulated by a varie

Substituted thiazole derivatives useful as platelet aggregation inhibitors

This invention relates to substituted thiazole derivatives of the following general formula, the substituent groups of which are as defined herein: STR1 These compounds are useful as inhibitors of platelet aggregation and inhibitors of adhesion molecules and may be provided in pharmaceutical compositions and in methods of treating reperfusion thrombosis injury in patients.