1599479-49-8

Basic information

• Product Name: {2-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethylsulphanyl]-quinolin-3-ylmethylene}-(4-[1,2,4]triazol-1-ylmethyl-phenyl)-amine
• Synonyms: {2-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethylsulphanyl]-quinolin-3-ylmethylene}-(4-[1,2,4]triazol-1-ylmethyl-phenyl)-amine
• CAS NO: 1599479-49-8
• Molecular Weight: 579.688
• Mol File: 1599479-49-8.mol

Chemical Properties

• CAS DataBase Reference: {2-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethylsulphanyl]-quinolin-3-ylmethylene}-(4-[1,2,4]triazol-1-ylmethyl-phenyl)-amine(CAS DataBase Reference)
• NIST Chemistry Reference: {2-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethylsulphanyl]-quinolin-3-ylmethylene}-(4-[1,2,4]triazol-1-ylmethyl-phenyl)-amine(1599479-49-8)
• EPA Substance Registry System: {2-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethylsulphanyl]-quinolin-3-ylmethylene}-(4-[1,2,4]triazol-1-ylmethyl-phenyl)-amine(1599479-49-8)

Safety Data

• Hazardous Substances Data: 1599479-49-8(Hazardous Substances Data)

Upstream product

• 2042-37-7 o-cyanobromobenzene 
• 119192-10-8 4-(1H-1,2,4-triazol-1-ylmethyl)aniline 
• 124750-53-4 N-triphenylmethyl-5-(4'-methylbiphenyl-2-yl)tetrazole 
• 120568-11-8 2-(tetrazol-5-yl)-4'-methyl-1,1'-biphenyl 
• 51925-41-8 3-formyl-2-mercaptoquinoline 
• 73568-25-9 2-chloro-3-quinoline carboxaldehyde 
• 103-84-4 Acetanilid 
• 124750-51-2 N-(triephenylmethyl)-5-<4'-(bromomethyl)-biphenyl-2-yl>tetrazole 
• 114772-53-1 2-Cyano-4'-methylbiphenyl 
• 5720-05-8 4-methylphenylboronic acid 

Relevant articles and documents

Synthesis of new biphenyl-substituted quinoline derivatives, preliminary screening and docking studies

New quinoline derivatives containing biphenyl ring were synthesized and characterized by IR, 1H NMR and mass spectral studies. The synthesized compounds were screened for antimicrobial, anthelmintic activities as well as free radical scavenging property against the DPPH radical. The minimum inhibition concentration values showed promising inhibiting activity and are potent biological agents. The compounds showed minimum binding energy towards β-tubulin. The compounds 11a, 11c, 13c and 13d have good affinity towards the active pocket and may be considered as a good inhibitor of β-tubulin.

Synthesis of new biphenyl-substituted quinoline derivatives, preliminary screening and docking studies

New quinoline derivatives containing biphenyl ring were synthesized and characterized by IR, 1H NMR and mass spectral studies. The synthesized compounds were screened for antimicrobial, anthelmintic activities as well as free radical scavenging property against the DPPH radical. The minimum inhibition concentration values showed promising inhibiting activity and are potent biological agents. The compounds showed minimum binding energy towards ?-tubulin. The compounds 11a, 11c, 13c and 13d have good affinity towards the active pocket and may be considered as a good inhibitor of β-tubulin. Indian Academy of Sciences.