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Guanosine, N-(4-butylphenyl)-2'-deoxy-, 5'-methanesulfonate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

160053-66-7

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160053-66-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 160053-66-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,0,0,5 and 3 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 160053-66:
(8*1)+(7*6)+(6*0)+(5*0)+(4*5)+(3*3)+(2*6)+(1*6)=97
97 % 10 = 7
So 160053-66-7 is a valid CAS Registry Number.

160053-66-7Relevant academic research and scientific papers

Synthesis of the P1, P2-methylene analog of N2-(p-n-butylphenyl)-2'- deoxyguanosine 5'-triphosphate: A non-substrate inhibitor of DNA polymerases

Yanachkov,Wright

, p. 339 - 350 (1994)

N2-(p-n-Butylphenyl)-2'-deoxyguanosine 5'-(P1, P2-methylene)- triphosphate (BuPdGMPCH2PP) has been synthesized. Displacement of the mesyloxy group of 5'-MesBuPdG by methanediphosphonate gave 30% of BuPdGMPCH2P, but 68% of 3,5'-cycloBuPdG. Reaction of the nucleoside BuPdG with methanediphosphonate and DCC gave 62% of BuPdGMPCH2PPCH2P, which was hydrolyzed to BuPdGMPCH2P in 77% yield. The title compound was obtained by reacting the imidazolide of BuPdGMPCH2P with orthophosphate. BuPdGMPCH2PP inhibited calf thymus DNA polymerase α with K(i) = 9.5 nM, a potency only fivefold weaker than that of BuPdGTP itself.

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