160058-93-5Relevant academic research and scientific papers
Transition-metal-catalyzed allylic substitution and titanocene-catalyzed epoxypolyene cyclization as a powerful tool for the preparation of terpenoids
Gansaeuer, Andreas,Justicia, Jose,Rosales, Antonio,Worgull, Dennis,Rinker, Bjoern,Cuerva, Juan Manuel,Oltra, Juan Enrique
, p. 4115 - 4127 (2007/10/03)
Many biologically active substances are composed of sesquiterpene units linked to aromatic structures, especially substituted phenols. Here, we describe an efficient synthetic approach to this class of natural product from commercially available substances in a short sequence. The key transformations involve allylic substitution reactions using a palladium or copper catalyst and titanocene-catalyzed epoxypolyene cyclization reactions via radicals. The polycyclic core structures are accessed with high chemo- and stereocontrol. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.
Synthetic studies towards complex diterpenoids. Part 20.1 Total synthesis of the linear abietane o-quinone umbrosone
Ghosh, Keya,Ghatak, Usha Ranjan
, p. 1359 - 1362 (2007/10/03)
A simple total synthesis of the rearranged linear abietane diterpenoid o-quinone, umbrosone 1, has been accomplished through fraH5-l,2, 3, 4, 9, 9a-hexahydro-l,l-dimethyl-6-methoxyanthracen-10(4a//)-one 12t.
First total synthesis of the linear abietane diterpenoid orthoquinone umbrosone
Ghosh, Keya,Ghatak, Usha Ranjan
, p. 5943 - 5944 (2007/10/02)
The first total synthesis of the rearranged linear abietane diterpenoid orthoquinone, umbrosone (1), was accomplished through a simple convergent route via the tricyclic ketone 11.
