160069-11-4

Upstream product

• 870-63-3 prenyl bromide 
• 107052-29-9 methyl 4'-benzyloxy-2'-(3-methylbut-2-enyloxy)cinnamate 
• 107052-38-0 7-(benzyloxy)-6-(3-methylbut-2-enyl)-2H-chromen-2-one 
• 107052-26-6 (E)-3-(4-Benzyloxy-2-hydroxy-phenyl)-acrylic acid methyl ester 
• 31005-04-6 7-(benzyloxy)-2H-chromen-2-one 
• 160069-10-3 methyl 4'-benzyloxy-2'-hydroxy-5'-(3-methylbut-2-enyl)cinnamate 
• 124-41-4 sodium methylate 

Downstream Products

• 72619-99-9 balsamiferone 
• 111931-24-9 7-benzyloxy-3,6-bis(3-methylbut-2-enyl)coumarin 

Relevant academic research and scientific papers

Tandem Thermal Claisen-Cope Rearrangements of Coumarate Derivatives. Total Syntheses of the Naturally Occuring Coumarins: Suberosin, Demethylsuberosin, Ostrithin, Balsamiferone and Gravelliferone

Thermal Claisen rearrangements of derivatives of 4'-O-methyl and 4'-O-benzyl methyl coumarates 3, prepared from the corresponding umbelliferone derivatives, have been investigated.Simple allyl derivatives rearrange predominantly to the vacant ortho-positi

An Iterative Procedure for the Synthesis of the Diprenylated Coumarins Balsamiferone and Gravelliferone from Umbelliferone via Multiple Sigmatropic Rearrangements

Repeated sequences of sigmatropic rearrangements initiated by a Claisen rearrangement permit the synthesis of the 3,6-disubstituted umbelliferone derivatives balsamiferone (4) and gravelliferone (6) from umbelliferone.