1601-81-6

Basic information

• Product Name: 2-benzoylcyclopropanecarboxylic acid
• Synonyms: 2-benzoylcyclopropanecarboxylic acid;cis-2-Benzoyl-cyclopropanecarboxylic acid
• CAS NO: 1601-81-6
• Molecular Formula: C₁₁H₁₀O₃
• Molecular Weight: 190.1953
• Mol File: 1601-81-6.mol

Chemical Properties

• Boiling Point: 369.8°Cat760mmHg
• Flash Point: 191.7°C
• Appearance: /
• Density: 1.334g/cm³
• Vapor Pressure: 4.01E-06mmHg at 25°C
• Refractive Index: 1.612
• CAS DataBase Reference: 2-benzoylcyclopropanecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzoylcyclopropanecarboxylic acid(1601-81-6)
• EPA Substance Registry System: 2-benzoylcyclopropanecarboxylic acid(1601-81-6)

Safety Data

• Hazardous Substances Data: 1601-81-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
2-Benzoylcyclopropanecarboxylic acid is used as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its unique structure and properties contribute to the development of new and effective compounds for medical and agricultural applications.
Used in Dye and Pigment Production:
2-Benzoylcyclopropanecarboxylic acid is utilized in the production of dyes and pigments, providing a wide range of colors and properties for various industries, such as textiles, plastics, and printing inks.
Used in Medicinal Chemistry:
Due to its unique structure, 2-benzoylcyclopropanecarboxylic acid has potential applications in medicinal chemistry, where it can be used to develop new drugs with improved efficacy and selectivity.
Used in Material Science:
2-Benzoylcyclopropanecarboxylic acid also has potential applications in material science, where its unique properties can be harnessed to create new materials with specific characteristics for various applications.
Safety and Disposal:
It is important to handle and dispose of 2-benzoylcyclopropanecarboxylic acid properly, as it can be hazardous to human health and the environment if not managed safely. Proper safety measures and disposal methods should be followed to minimize any potential risks associated with 2-benzoylcyclopropanecarboxylic acid.

InChI:InChI=1/C11H10O3/c12-10(7-4-2-1-3-5-7)8-6-9(8)11(13)14/h1-5,8-9H,6H2,(H,13,14)

Upstream product

• 6366-29-6 2-benzoyl-cyclopropane-1,1-dicarboxylic acid 
• 5617-74-3 3-oxabicyclo[3.1.0]hexane-2,4-dione 
• 71-43-2 benzene 
• 97427-59-3 dimethyl 2-benzoylcyclopropane-1,1-dicarboxylate 
• 97427-62-8 4,4-bismethoxycarbonyl-1-oxo-1-phenylbutane 
• 936-59-4 3-chloropropiophenone 
• 5617-74-3 cis-1,2-cyclopropanedicarboxylic acid anhydride 

Downstream Products

• 21769-53-9 3-(2-morpholin-4-yl-ethyl)-5-phenyl-3,4-diaza-bicyclo[4.1.0]hept-4-en-2-one 
• 1501-05-9 5-oxo-5-phenylvaleric acid 

Relevant articles and documents

A General Protocol for Radical Anion [3+2] Cycloaddition Enabled by Tandem Lewis Acid Photoredox Catalysis

A method for intermolecular [3+2] cycloaddition between aryl cyclopropyl ketones and alkenes involving the combination of Lewis acid and photoredox catalysis is reported. In contrast to other more common methods for [3+2] cycloaddition, these conditions o

Enantioselective Photocatalytic [3 + 2] Cycloadditions of Aryl Cyclopropyl Ketones

Control of stereochemistry in photocycloaddition reactions remains a substantial challenge; almost all successful catalytic examples to date have involved [2 + 2] photocycloadditions of enones. We report a method for the asymmetric [3 + 2] photocycloaddition of aryl cyclopropyl ketones that enables the enantiocontrolled construction of densely substituted cyclopentane structures not synthetically accessible using other catalytic methods. These results show that the dual-catalyst strategy developed in our laboratory broadens synthetic chemists' access to classes of photochemical cycloadditions that have not previously been feasible in enantioselective form.