97427-59-3

Upstream product

• 97427-62-8 4,4-bismethoxycarbonyl-1-oxo-1-phenylbutane 
• 90484-46-1 2-bromo-1-phenylprop-2-en-1-one 
• 108-59-8 malonic acid dimethyl ester 
• 879-72-1 3-(dimethylamino)propiophenone hydrochloride 
• 936-59-4 3-chloropropiophenone 
• 29636-75-7 3-bromo-1-phenylpropan-1-one 
• 71-43-2 benzene 
• 768-03-6 Phenyl vinyl ketone 
• 97427-58-2 methyl 4-bromo-5-oxo-2-bis(methoxycarbonyl)-5-phenylpentanoate 

Downstream Products

• 1601-82-7 (+/-)-trans-2-benzoyl-cyclopropane-carboxylic acid-⁽¹⁾ 
• 1601-81-6 cis 2-benzoylcyclopropanecarboxylic acid 
• 6366-29-6 2-benzoyl-cyclopropane-1,1-dicarboxylic acid 

Relevant academic research and scientific papers

Anodic cyclization of dimethyl 2-(3-Oxo-3-arylpropyl) malonates into the corresponding dimethyl 2-aroylcyclopropane-1,1-dicarboxylates

A variety of dimethyl 2-(3-oxo-3-arylpropyl)malonates were electrooxidized in methanol, in the presence of potassium iodide and a base or a neutral salt, to give the corresponding cyclized dimethyl 2-aroylcyclopropane-1,1- dicarboxylates in moderate to good yields. The reactions were carried out under extremely mild reaction conditions, in which the optimal amount of electrolytic current varied from 2.12-2.41 F·mol-1 depending on the substrates. The reaction presumably proceeds via a two-electron oxidation process, in which iodide ions play an important role as the electron carrier between the anode and the substrate. Georg Thieme Verlag Stuttgart. New York.

Stereoselectivity in the Michael Reaction. II. Stereochemistry of a Heavily Substituted Alkene

The trimethylsilylated primary Michael adduct of tricarbomethoxymethane and 2-bromo-3-oxo-3-phenylpropene-1 is shown by 1H NMR experiments and X-ray diffraction studies to possess the structure Z-2.Attempts to prepare the E isomer via the hydrolysis product of Z-2 resulted in, inter alia, an intramolecular alkylation under decarbomethoxylation to give the cyclopropane ester 4.