160168-15-0

Upstream product

• 160062-54-4 ethyl 1R-(1α,2α,4α)-4-hydroxy-2-methyl-cyclohexanecarboxylate 
• 62617-91-8 ethyl 2-methyl-4-oxocyclohexane-1-carboxylate 
• 487-51-4 4-carbethoxy-3-methyl-2-cyclohexen-1-one 
• 49617-26-7 rac-(1S,2R)-ethyl 2-methyl-4-oxocyclohexanecarboxylate 

Relevant academic research and scientific papers

PYRAZOLE AMIDE DERIVATIVE

The present invention relates to a novel compound having a function of inhibiting RORγ activity. The present invention also relates to pharmaceutical composition comprising the compound, a use of the compound in treating or preventing autoimmune diseases, inflammatory diseases, metabolic diseases, or cancer diseases.

Enantioselective synthesis of the hexahydronaphthalene nucleus of (-)-compactin from ethyl (1R,2S)-2-methyl-4-oxocyclohexanecarboxylate and 2-(3-nitropropyl)-1,3-dioxolane as four carbon bifunctional annelating agent

An enantioselective approach to the synthesis of the hexahydronaphthalene nucleus of natural compactin is described. The key elements of the synthesis are as follows: (i) the preparation of the chiral starting material through enzymatic resolution of the