160168-16-1

Upstream product

• 186581-53-3 diazomethane 
• 62617-91-8 ethyl 2-methyl-4-oxocyclohexane-1-carboxylate 

Downstream Products

• 160062-72-6 <1S<1α(S*),5αβ,7β,8β,8aβ>>-2-methylbutanoic acid 8-benzyloxymethyl-5-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-7-methyl-1,2,3,5,6,7,8,8a-octahydro-1-naphthalenyl ester 
• 160062-70-4 <1R-(1α,2α,4αβ,8aα)>-1-benzyloxymethyl-4-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-methyl-1,2,3,4,6,7-hexahydro-<8aH>-naphthalen-8-one 
• 160062-73-7 <1S<1α(S*),5αβ,7β,8β,8aβ>>-2-methylbutanoic acid 8-benzyloxymethyl-5-hydroxy-7-methyl-1,2,3,5,6,7,8,8a-octahydro-1-naphthalenyl ester 
• 160062-74-8 <1S<1α(S*),7β,8β,8aβ>>-2-methylbutanoic acid 8-benzyloxymethyl-1,2,3,7,8,8a-hexahydro-7-methyl-naphthalenyl ester 
• 160062-71-5 <1R-(1α,2α,4αβ,8β,8aα)>-1-benzyloxymethyl-4-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-methyl-1,2,3,4,6,7,8,8a-octahydronaphthalen-4-ol 
• 160062-69-1 (5S,7S,8S,8aR)-8-Benzyloxymethyl-5-hydroxy-7-methyl-3,5,6,7,8,8a-hexahydro-2H-naphthalen-1-one oxime 
• 160062-68-0 <1R-(1α,2α,4αβ,8αβ,8aα)>-1-benzyloxymethyl-4-hydroxy-2-methyl-1,2,3,4,6,7-hexahydro-<8aH>-naphthalen-8-one 
• 160062-57-7 <7R-(7α,8α)>-(-)-7-benzyloxymethyl-8-methyl-1,4-dioxaspiro<4,5>decane 
• 160062-62-4 (+)-4-<(Benzyloxy)methyl>-3-methyl-2-cyclohexen-1-one 
• 160062-61-3 <4S-(4α,5α)>-(-)-4-benzyloxymethyl-5-methyl-2-cyclohexen-1-one 
• 160062-58-8 <3R-(3α,4α)>-(-)-4-benzyloxymethyl-3-methylcyclohexanone 

Relevant academic research and scientific papers

Enantioselective synthesis of the hexahydronaphthalene nucleus of (-)-compactin from ethyl (1R,2S)-2-methyl-4-oxocyclohexanecarboxylate and 2-(3-nitropropyl)-1,3-dioxolane as four carbon bifunctional annelating agent

An enantioselective approach to the synthesis of the hexahydronaphthalene nucleus of natural compactin is described. The key elements of the synthesis are as follows: (i) the preparation of the chiral starting material through enzymatic resolution of the