160062-61-3Relevant academic research and scientific papers
Enantioselective synthesis of the hexahydronaphthalene nucleus of (-)-compactin from ethyl (1R,2S)-2-methyl-4-oxocyclohexanecarboxylate and 2-(3-nitropropyl)-1,3-dioxolane as four carbon bifunctional annelating agent
Barco,Benetti,Bianchi,Casolari,Pollini,Romagnoli,Spalluto,Zanirato
, p. 11743 - 11754 (2007/10/02)
An enantioselective approach to the synthesis of the hexahydronaphthalene nucleus of natural compactin is described. The key elements of the synthesis are as follows: (i) the preparation of the chiral starting material through enzymatic resolution of the
