16017-30-4

Basic information

• Product Name: 1-ETHYNYL-2,4-DIMETHYL-BENZENE
• Synonyms: 1-ETHYNYL-2,4-DIMETHYL-BENZENE;Benzene, 1-ethynyl-2,4-dimethyl- (9CI);Benzene, 1-ethynyl-2,4-dimethyl-;Ethynyl-2,4-dimethylbenzene
• CAS NO: 16017-30-4
• Molecular Formula: C₁₀H₁₀
• Molecular Weight: 130.1864
• Mol File: 16017-30-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 189.7°Cat760mmHg
• Flash Point: 56.7°C
• Appearance: /
• Density: 0.93g/cm³
• Vapor Pressure: 0.778mmHg at 25°C
• Refractive Index: 1.528
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-ETHYNYL-2,4-DIMETHYL-BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ETHYNYL-2,4-DIMETHYL-BENZENE(16017-30-4)
• EPA Substance Registry System: 1-ETHYNYL-2,4-DIMETHYL-BENZENE(16017-30-4)

Safety Data

• Hazardous Substances Data: 16017-30-4(Hazardous Substances Data)

Usage

General Description

1-Ethynyl-2,4-dimethyl-benzene is a chemical compound that belongs to the family of aromatic hydrocarbons. Its molecular formula is C10H10, and it is characterized by its structure composed of a benzene ring substituted by an ethynyl group and two methyl groups. This organic compound is generally considered stable, but it can react with several types of chemical substances, making it useful in various industrial applications and chemical research. As is the case with many synthetic chemicals, safety precautions should be implemented while handling 1-ethynyl-2,4-dimethyl-benzene due to its potential hazards.

InChI:InChI=1/C10H10/c1-4-10-6-5-8(2)7-9(10)3/h1,5-7H,2-3H3

Upstream product

• 15764-16-6 2,4-dimethylbenzaldehyde 
• 4214-28-2 1-iodo-2,4-dimethylbenzene 
• 562813-14-3 ((2,4-dimethylphenyl)ethynyl)trimethylsilane 
• 16017-29-1 1-(1,1-Dichloro-ethyl)-2,4-dimethyl-benzene 
• 74346-30-8 1-(2,4-Dimethylphenyl)vinyl chloride 
• 583-70-0 1-bromo-2,4-dimethylbenzene 
• 89-74-7 2,4-dimethylacetophenone. 

Downstream Products

• 861778-19-0 1,4-bis(2,4-dimethylphenyl)buta-1,3-diyne 
• 61440-87-7 C₁₈H₁₈ 
• 1564265-62-8 methyl 4-(3,4-bis(2,4-dimethylphenyl)-2-(ethoxycarbonyl)-5-oxocyclopenta-1,3-dien-1-yl)benzoate 
• 1564265-63-9 ethyl 4,5-bis(2,4-dimethylphenyl)-2-(4-ethylphenyl)-3-oxocyclopenta-1,4-dienecarboxylate 
• 1564265-64-0 ethyl 4,5-bis(2,4-dimethylphenyl)-2-(4-methoxyphenyl)-3-oxocyclopenta-1,4-di-enecarboxylate 
• 1564265-65-1 ethyl 2-([1,1'-biphenyl]-4-yl)-4,5-bis(2,4-dimethylphenyl)-3-oxocyclopenta-1,4-di-enecarboxylate 
• 1564265-66-2 ethyl 4,5-bis(2,4-dimethylphenyl)-3-oxo-2-m-tolylcyclopenta-1,4-dienecarboxylate 
• 1564265-67-3 ethyl 4,5-bis(2,4-dimethylphenyl)-2-(naphthalen-2-yl)-3-oxocyclopenta-1,4-diene-carboxylate 
• 1564265-54-8 ethyl 4,5-bis(2,4-dimethylphenyl)-3-oxo-2-phenylcyclopenta-1,4-dienecarboxylate 
• 1564265-72-0 methyl 4,5-bis(2,4-dimethylphenyl)-3-oxo-2-phenylcyclopenta-1,4-dienecarboxylate 
• 1564265-55-9 ethyl 4,5-bis(2,4-dimethylphenyl)-2-(4-fluorophenyl)-3-oxocyclopenta-1,4-diene-carboxylate 
• 1564265-56-0 ethyl 2-(4-chlorophenyl)-4,5-bis(2,4-dimethylphenyl)-3-oxocyclopenta-1,4-diene-carboxylate 
• 1564265-57-1 ethyl 2-(4-bromophenyl)-4,5-bis(2,4-dimethylphenyl)-3-oxocyclopenta-1,4-diene-carboxylate 
• 1564265-58-2 ethyl 4,5-bis(2,4-dimethylphenyl)-3-oxo-2-(4-(trifluoromethyl)phenyl)cyclopenta-1,4-dienecarboxylate 

Relevant articles and documents

Metal-free synthesis of imidazole by BF3·Et2O promoted denitrogenative transannulation of N-sulfonyl-1,2,3-triazole

BF3·Et2O promoted metal-free denitrogenative transannulation of N-sulfonyl-1,2,3-triazole was reported. Rather than transition metals, BF3·Et2O was employed for the first time to promote the formation of α-diazoimines from N-sulfonyl-1,2,3-triazoles in nitriles, leading to the synthesis of various imidazoles. The protocol tolerates a broad range of functional groups and could also be applied to the late-stage modification of bioactive molecules, demonstrating the potential of this protocol in organic synthesis. A plausible mechanism was proposed.

COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with Toll-Like Receptors, including TLR7 and TLR8. In one aspect, the compounds are useful as adjuvants for enhancing the effectiveness of a vaccine (formula I) wherein: X3 is N; X4 is N Or CR3; X5 is -CR4=CR5.

Choix des methodes pour la synthese univoque de carbures acetyleniques. Troisieme partie : Arylacetylenes et aryl-1 alcynes-1

The range of applicability of six syntheses of pure alkynes with one aryl group has been defined; a short review of other possible procedures is included.We have specified the best method to obtain selectively the alkynes Ar-CCH and Ar-CC-R, according to the nature of the substituents of the aryl group and according to the developed structure of the R group.It is thus possible to recommend with the largest probability of success the method to obtain, in homogenous series, alkynes corresponding to still more complicated structures.