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Granisetron Impurity C is a light yellow powder that serves as an impurity in the synthesis of Granisetron Hydrochloride, a medication used to prevent nausea and vomiting caused by certain types of chemotherapy or surgery.

160177-67-3

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160177-67-3 Usage

Uses

Used in Pharmaceutical Industry:
Granisetron Impurity C is used as a synthesis impurity for Granisetron Hydrochloride production. Its presence is essential in the manufacturing process of the medication, which aims to alleviate the symptoms of nausea and vomiting in patients undergoing specific treatments.

Check Digit Verification of cas no

The CAS Registry Mumber 160177-67-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,0,1,7 and 7 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 160177-67:
(8*1)+(7*6)+(6*0)+(5*1)+(4*7)+(3*7)+(2*6)+(1*7)=123
123 % 10 = 3
So 160177-67-3 is a valid CAS Registry Number.
InChI:InChI=1/C17H22N4O/c1-21-15-8-3-2-7-14(15)16(20-21)17(22)19-13-9-11-5-4-6-12(10-13)18-11/h2-3,7-8,11-13,18H,4-6,9-10H2,1H3,(H,19,22)

160177-67-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(9-azabicyclo[3.3.1]nonan-3-yl)-1-methylindazole-3-carboxamide

1.2 Other means of identification

Product number -
Other names 9'-Desmethyl-Granisetron

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:160177-67-3 SDS

160177-67-3Downstream Products

160177-67-3Relevant academic research and scientific papers

Efficient syntheses of exo-granisetron hydrochloride and other potential impurities present in granisetron hydrochloride, an anti-emetic drug

Vishnu, Eda V.R.,Joseph, Suju,Srinivasana, Abayee K.,Gania, Ramesh S.,Reddy, Govindabur R.,Rao, Patakokila V.,Dahanukara, Vilas H.,Ramanatham, Josyula,Devanna, Nayakanti

experimental part, p. 722 - 727 (2012/05/04)

European Pharmacopeia mentions about nine potential impurities in Granisetron hydrochloride. These impurities need to be controlled in the API as described in the Pharmacopeia. Elegant syntheses of four potential impurities in Granisetron hydrochloride are disclosed.

Synthesis and gastrointestinal prokinetic activity of novel benzamide derivatives with amphoteric side chains

Sakaguchi,Iwasaki,Iwanaga,Saito,Takahara,Kato,Hanaoka

, p. 424 - 436 (2007/10/03)

Novel benzamide derivatives (19-24, 32a-c, 43d-f), each possessing a cycloaminoalkanecarboxylic acid side chain, were synthesized and their gastrointestinal prokinetic and dopamine D2 receptor antagonist activities were evaluated. 4-[(4-Amino-5

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