16018-83-0 Usage
General Description
1-(4-Fluorophenyl)biguanide hydrochloride, also known as 4-Fluorophenylbiguanide Hydrochloride, is a chemical compound that is commonly used in chemical and pharmaceutical research. It is chiefly employed as an intermediate in the chemical synthesis of several biologically active substances. It is part of the biguanide family, which is known for their biological activity such as antimalarial, antifungal and antimicrobial properties. Its structure contains a Fluorine atom, which has a reputation for enhancing biological activity in compounds. It is a solid substance with a significant molecular weight, and it is characterised by its white color. The hydrochloride salt form makes it water-soluble and easy to work with.
Check Digit Verification of cas no
The CAS Registry Mumber 16018-83-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,0,1 and 8 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 16018-83:
(7*1)+(6*6)+(5*0)+(4*1)+(3*8)+(2*8)+(1*3)=90
90 % 10 = 0
So 16018-83-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H10FN5.ClH/c9-5-1-3-6(4-2-5)13-8(12)14-7(10)11;/h1-4H,(H6,10,11,12,13,14);1H
16018-83-0Relevant articles and documents
BIGUANIDE COMPOUNDS AND USE THEREOF
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Paragraph 0524-0531, (2021/02/16)
The present invention relates to a biguanide compound and uses thereof. More specifically, the present invention relates to: a biguanide derivative exhibiting excellent effects in inhibiting cancer cell proliferation, cancer metastasis, and cancer recurrence; a manufacturing method of the biguanide derivative; and a pharmaceutical composition containing the biguanide derivative as an active component.
NOVEL CYCLIC GMP-AMP SYNTHASE (CGAS) INHIBITORS AND THEIR METHOD OF USE
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Page/Page column 64-65, (2020/01/08)
Methods of treating diseases related to cGAS activation. Small molecule inhibitors of cGAS and pharmaceutical compositions and uses thereof in treating autoimmune diseases or inflammation.
