16019-34-4

Basic information

• Product Name: 7-BENZYL-4-CHLORO-7H-PYRROLO[2,3-D] PYRIMIDINE
• Synonyms: 7-BENZYL-4-CHLORO-7H-PYRROLO[2,3-D] PYRIMIDINE
• CAS NO: 16019-34-4
• Molecular Formula: C₁₃H₁₀ClN₃
• Molecular Weight: 243.69
• Mol File: 16019-34-4.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 7-BENZYL-4-CHLORO-7H-PYRROLO[2,3-D] PYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-BENZYL-4-CHLORO-7H-PYRROLO[2,3-D] PYRIMIDINE(16019-34-4)
• EPA Substance Registry System: 7-BENZYL-4-CHLORO-7H-PYRROLO[2,3-D] PYRIMIDINE(16019-34-4)

Safety Data

• Hazardous Substances Data: 16019-34-4(Hazardous Substances Data)

Upstream product

• 100-44-7 benzyl chloride 
• 3680-69-1 4-chloro-1H-pyrrolo[2,3-d]pyrimidine 
• 100-39-0 benzyl bromide 
• 186519-89-1 7-(benzenesulfonyl)-4-chloro-7H-pyrrolo[2,3-d]pyrimidine 
• 100-51-6 benzyl alcohol 

Downstream Products

• 1398560-69-4 C₁₉H₁₆N₄O 

Relevant articles and documents

4,7-disubstituted 7h-pyrrolo[2,3-d]pyrimidines and their analogs as antiviral agents against zika virus

Discovery of compound 1 as a Zika virus (ZIKV) inhibitor has prompted us to investigate its 7H-pyrrolo[2,3-d]pyrimidine scaffold, revealing structural features that elicit antiviral activity. Furthermore, we have demonstrated that 9H-purine or 1H-pyrazolo[3,4-d]pyrimidine can serve as an alternative core structure. Overall, we have identified 4,7-disubstituted 7H-pyrrolo[2,3-d]pyrimidines and their analogs including compounds 1, 8 and 11 as promising antiviral agents against flaviviruses ZIKV and dengue virus (DENV). While the molecular target of these compounds is yet to be elucidated, 4,7-disubstituted 7H-pyrrolo[2,3-d]pyrimidines and their analogs are new chemotypes in the design of small molecules against flaviviruses, an important group of human pathogens.

Novel drug-like somatostatin receptor 4 agonists are potential analgesics for neuropathic pain

Somatostatin released from the capsaicin-sensitive sensory nerves mediates analgesic and anti-inflammatory effects via the somatostatin sst4 receptor without endocrine actions. Therefore, sst4 is considered to be a novel target for d

Pyrrolo[2,3-d]pyrimidine compounds

A compound of the formula wherein R1, R2 and R3 are as defined above, which are inhibitors of the enzyme protein tyrosine kinases such as Janus Kinase 3 and as such are useful therapy as immunosuppressive agents for organ transplants, lupus, multiple sclerosis, rheumatoid arthritis, psoriasis, Type I diabetes and complications from diabetes, cancer, asthma, atopic dermatitis, autoimmune thyroid disorders, ulcerative colitis, Crohn's disease, Alzheimer's disease, Leukemia and other autoimmune diseases.