160231-42-5

Basic information

• Product Name: [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[cyclopentylmethyl-(4-methoxyphenyl)su lfonyl-amino]-3-hydroxy-1-phenyl-butan-2-yl]carbamate
• Synonyms: [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[cyclopentylmethyl-(4-methoxyphenyl)su lfonyl-amino]-3-hydroxy-1-phenyl-butan-2-yl]carbamate
• CAS NO: 160231-42-5
• Molecular Formula: C28H38N2O7S
• Molecular Weight: 546.68
• Mol File: 160231-42-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Density: 1.3g/cm³
• Refractive Index: 1.605
• CAS DataBase Reference: [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[cyclopentylmethyl-(4-methoxyphenyl)su lfonyl-amino]-3-hydroxy-1-phenyl-butan-2-yl]carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[cyclopentylmethyl-(4-methoxyphenyl)su lfonyl-amino]-3-hydroxy-1-phenyl-butan-2-yl]carbamate(160231-42-5)
• EPA Substance Registry System: [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[cyclopentylmethyl-(4-methoxyphenyl)su lfonyl-amino]-3-hydroxy-1-phenyl-butan-2-yl]carbamate(160231-42-5)

Safety Data

• Hazardous Substances Data: 160231-42-5(Hazardous Substances Data)

Usage

General Description

The chemical compound "[(3S)-oxolan-3-yl] N-[(2S,3R)-4-[cyclopentylmethyl-(4-methoxyphenyl)su lfonyl-amino]-3-hydroxy-1-phenyl-butan-2-yl]carbamate" is a complex molecule with multiple functional groups. It contains an oxolan-3-yl group, a carbamate group, and a phenylsulfonyl-amino group, among others. The compound also contains a cyclopentylmethyl and a methoxyphenyl functional group. [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[cyclopentylmethyl-(4-methoxyphenyl)su lfonyl-amino]-3-hydroxy-1-phenyl-butan-2-yl]carbamate is likely to have biological activity due to the presence of the hydroxy group and the various aromatic rings, making it a potential pharmaceutical or medicinal compound. The stereochemistry of the molecule, indicated by the (3S), (2S), and (3R) in the name, suggests that the compound has specific three-dimensional structure and potential interactions with biological molecules.

InChI:InChI=1/C28H38N2O7S/c1-35-23-11-13-25(14-12-23)38(33,34)30(18-22-9-5-6-10-22)19-27(31)26(17-21-7-3-2-4-8-21)29-28(32)37-24-15-16-36-20-24/h2-4,7-8,11-14,22,24,26-27,31H,5-6,9-10,15-20H2,1H3,(H,29,32)/t24-,26-,27+/m0/s1

Upstream product

• 160232-71-3 C₂₁H₃₂N₂O₄ 
• 98-68-0 4-methoxy-phenyl-sulphonyl chloride 

Relevant articles and documents

Sulfonamide inhibitors of aspartyl protease

The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical features. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting HIV-1 and HIV-2 protease activity and consequently, may be advantageously used as anti-viral agents against the HIV-1 and HIV-2 viruses. This invention also relates to methods for inhibiting the activity of HIV aspartyl protease using the compounds of this invention and methods for screening compounds for anti-HIV activity.

SULFONAMIDE INHIBITORS OF ASPARTYL PROTEASE

The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical features. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting HIV-1 and HIV-2 protease activity and consequently, may be advantageously used as anti-viral agents against the HIV-1 and HIV-2 viruses. This invention also relates to methods for inhibiting the activity of HIV aspartyl protease using the compounds of this invention and methods for screening compounds for anti-HIV activity.