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1602747-35-2

N-(3,5-di-tert-butylphenyl)-2-(2-phenyl-1H-benzo[d]imidazol-1-yl)acetamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1602747-35-2 Structure

  • Basic information

    1. Product Name: N-(3,5-di-tert-butylphenyl)-2-(2-phenyl-1H-benzo[d]imidazol-1-yl)acetamide
    2. Synonyms: N-(3,5-di-tert-butylphenyl)-2-(2-phenyl-1H-benzo[d]imidazol-1-yl)acetamide
    3. CAS NO:1602747-35-2
    4. Molecular Formula:
    5. Molecular Weight: 439.601
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1602747-35-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N-(3,5-di-tert-butylphenyl)-2-(2-phenyl-1H-benzo[d]imidazol-1-yl)acetamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: N-(3,5-di-tert-butylphenyl)-2-(2-phenyl-1H-benzo[d]imidazol-1-yl)acetamide(1602747-35-2)
    11. EPA Substance Registry System: N-(3,5-di-tert-butylphenyl)-2-(2-phenyl-1H-benzo[d]imidazol-1-yl)acetamide(1602747-35-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1602747-35-2(Hazardous Substances Data)

1602747-35-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1602747-35-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,0,2,7,4 and 7 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1602747-35:
(9*1)+(8*6)+(7*0)+(6*2)+(5*7)+(4*4)+(3*7)+(2*3)+(1*5)=152
152 % 10 = 2
So 1602747-35-2 is a valid CAS Registry Number.

1602747-35-2Downstream Products

1602747-35-2Relevant articles and documents

Discovery of benzimidazole derivatives as modulators of mitochondrial function: A potential treatment for Alzheimer's disease

Kim, TaeHun,Yang, Ha Yun,Park, Beoung Gun,Jung, Seo Yun,Park, Jong-Hyun,Park, Ki Duk,Min, Sun-Joon,Tae, Jinsung,Yang, Hyejin,Cho, Suengmok,Cho, Sung Jin,Song, Hyundong,Mook-Jung, Inhee,Lee, Jiyoun,Pae, Ae Nim

, p. 1172 - 1192 (2016/11/23)

In this study, we designed a library of compounds based on the structures of well-known ligands of the 18 kDa translocator protein (TSPO), one of the putative components of the mPTP. We performed diverse mitochondrial functional assays to assess their ability to restore cells from Aβ-induced toxicity in vitro and in vivo. Among tested compounds, compound 25 effectively improved cognitive function in animal models of AD. Given the excellent in vitro and in vivo activity and a favorable pharmacokinetic profile of compound 25, we believe that it can serve as a promising lead compound for a potential treatment option for AD.

BENZIMIDAZOLE DERIVATIVES AS MITOCHONDRIAL FUNCTION MODULATORS

-

, (2014/05/07)

Provided are a benzimidazole derivative modulating mitochondrial functions and having pharmaceutical activity as a neuro-protective agent, and a pharmaceutical composition including the compound as an active ingredient.

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