160310-47-4

Upstream product

• 1013326-40-3 (E)-4-(4-methoxybenzyloxy)-3-methyl-but-2-en-1-ol 
• 1013326-39-0 (E)-ethyl 4-(4-methoxybenzyloxy)-3-methylbut-2-enoate 
• 1421136-06-2 ((2S,3S)-3-((4-methoxybenzyloxy)methyl)-3-methyloxiran-2-yl)methanol 
• 917-54-4 methyllithium 
• 60856-64-6 (R)-2-(2,2-dimethyl-1,3-dioxolan-4-yl)-2-methylpropan-1-ol 
• 599-04-2 (R)-Pantolacton 
• 60856-63-5 (2R)-(-)-3,3-dimethylbutane-1,2,4-triol 
• 104708-08-9 2-((R)-2,2-Diethyl-[1,3]dioxolan-4-yl)-2-methyl-propan-1-ol 
• 824-94-2 p-methoxybenzyl chloride 

Downstream Products

• 135413-38-6 (3S,5R,7S)-7-benzyloxy-1-tert-butyldiphenylsiloxy-9-(p-methoxyphenyl)methoxy-8,8-dimethylnonane-3,5-diol 
• 135304-51-7 (3S,7S)-7-benzyloxy-1-(tert-butyldiphenylsiloxy)-9-(p-methoxyphenyl)methoxy-8,8-dimethyl-5,5-(trimethylenedithio)nonan-3-ol 
• 135304-57-3 (3S,5R,7S)-3-benzyloxy-9-tert-butyldiphenylsiloxy-1-(p-methoxyphenyl)methoxy-2,2-dimethyl-5,7-isopropylidenedioxynonane 
• 885674-86-2 (S)-1-(4-methoxybenzyloxy)-2,2-dimethylhex-5-en-3-ol 
• 135304-49-3 (2R)-1,2-epoxy-4-(p-methoxyphenyl)methoxy-3,3-dimethylbutane 

Relevant academic research and scientific papers

The first stereoselective total synthesis of nicotlactone A

Herein we report the first stereoselective total synthesis of nicotlactone A via acid catalyzed acetonide deprotection followed by intramolecular lactonization in one pot as the key step.

Bryostatins: The asymmetric synthesis of the C1-C9 and C17-C27 fragments

The construction of the fragments C1-C9 3 and C17-C27 4a of the bryostatins in an enantioselective and highly diastereoselective fashion is described. The usefulness of the 'chiron' approach is illustrated with

Bryostatins: The asymmetric synthesis of C1-C9 and C11-C16 fragments

The fragments C1-C9 19 and C11-C16 26 of the bryostatins are constructed in an enantioselective and highly diastereoselective fashion from respectively D-pantolactone (2) and L-erythrulose (3) as chiral template