135413-38-6Relevant articles and documents
The evolution of a stereoselective synthesis of the C1-C16 fragment of bryostatins
Ball, Matthew,Baron, Anne,Bradshaw, Ben,Dumeunier, Rapha?l,O'Brien, Matthew,Thomas, Eric J.
, p. 9650 - 9681 (2016/10/22)
The development of a synthesis of the C1-C16 fragment of bryostatins in which the key step is a stereoselective oxy-Michael reaction used to assemble the cis-2,6-disubstituted tetrahydropyran with the exocyclic alkene already installed, is described. Foll
Bryostatins: The asymmetric synthesis of the C1-C9 and C17-C27 fragments
De Brabander,Vandewalle
, p. 855 - 865 (2007/10/02)
The construction of the fragments C1-C9 3 and C17-C27 4a of the bryostatins in an enantioselective and highly diastereoselective fashion is described. The usefulness of the 'chiron' approach is illustrated with