1603835-87-5

Basic information

• Product Name: (S)-4-amino-5-azido-O-tert-butyldiphenylsilyl-1-pentanol
• CAS NO: 1603835-87-5
• Molecular Weight: 382.581
• Mol File: 1603835-87-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-4-amino-5-azido-O-tert-butyldiphenylsilyl-1-pentanol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-amino-5-azido-O-tert-butyldiphenylsilyl-1-pentanol(1603835-87-5)
• EPA Substance Registry System: (S)-4-amino-5-azido-O-tert-butyldiphenylsilyl-1-pentanol(1603835-87-5)

Safety Data

• Hazardous Substances Data: 1603835-87-5(Hazardous Substances Data)

Upstream product

• 1603835-84-2 (S)-5-azido-4-tert-butoxycarbonylamino-1-pentanol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 672883-28-2 4-tert-butoxycarbonylamino-5-methanesulfonyloxy-pentanoic acid methyl ester 
• 126587-35-7 methyl (4S)-4-[(tert-butoxy)carbonylamino]-5-hydroxypentanoate 
• 330680-83-6 methyl (4S)-5-azido-4-[(tert-butoxycarbonyl)amino]pentanoate 

Downstream Products

• 1603835-90-0 (S)-N-(1-azidomethyl-4-O-tert-butyldiphenylsilyloxybutyl)-N-2-cyanoethyl diethylphosphonoacetamide 

Relevant articles and documents

Function-oriented synthesis of liponucleoside antibiotics

Function-oriented synthesis of a class of liponucleoside antibiotics was investigated through rational simplification guided by previous structure-activity relationship studies of caprazamycins and muraymycins to address the issue associated with their molecular complexity. A lactam-fused isoxazolidine scaffold was designed, and a diverse set of lactam-fused isoxazolidines derivatives were constructed by intramolecular 1,3-dipolar cycloaddition of alkenyl nitrones. Several analogues exhibited moderate activity against a range of Gram-positive drug-resistant bacterial pathogens.