1603835-90-0

Basic information

• Product Name: (S)-N-(1-azidomethyl-4-O-tert-butyldiphenylsilyloxybutyl)-N-2-cyanoethyl diethylphosphonoacetamide
• Synonyms: (S)-N-(1-azidomethyl-4-O-tert-butyldiphenylsilyloxybutyl)-N-2-cyanoethyl diethylphosphonoacetamide
• CAS NO: 1603835-90-0
• Molecular Weight: 613.769
• Mol File: 1603835-90-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-N-(1-azidomethyl-4-O-tert-butyldiphenylsilyloxybutyl)-N-2-cyanoethyl diethylphosphonoacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-N-(1-azidomethyl-4-O-tert-butyldiphenylsilyloxybutyl)-N-2-cyanoethyl diethylphosphonoacetamide(1603835-90-0)
• EPA Substance Registry System: (S)-N-(1-azidomethyl-4-O-tert-butyldiphenylsilyloxybutyl)-N-2-cyanoethyl diethylphosphonoacetamide(1603835-90-0)

Safety Data

• Hazardous Substances Data: 1603835-90-0(Hazardous Substances Data)

Upstream product

• 330680-83-6 methyl (4S)-5-azido-4-[(tert-butoxycarbonyl)amino]pentanoate 
• 3095-95-2 diethylphosphonoacetic acid 
• 1603835-87-5 (S)-4-amino-5-azido-O-tert-butyldiphenylsilyl-1-pentanol 
• 126587-35-7 methyl (4S)-4-[(tert-butoxy)carbonylamino]-5-hydroxypentanoate 
• 672883-28-2 4-tert-butoxycarbonylamino-5-methanesulfonyloxy-pentanoic acid methyl ester 
• 1603835-84-2 (S)-5-azido-4-tert-butoxycarbonylamino-1-pentanol 

Relevant articles and documents

Function-oriented synthesis of liponucleoside antibiotics

Function-oriented synthesis of a class of liponucleoside antibiotics was investigated through rational simplification guided by previous structure-activity relationship studies of caprazamycins and muraymycins to address the issue associated with their molecular complexity. A lactam-fused isoxazolidine scaffold was designed, and a diverse set of lactam-fused isoxazolidines derivatives were constructed by intramolecular 1,3-dipolar cycloaddition of alkenyl nitrones. Several analogues exhibited moderate activity against a range of Gram-positive drug-resistant bacterial pathogens.