126587-35-7

Basic information

• Product Name: (S)-METHYL 4-(TERT-BUTOXYCARBONYLAMINO)-5-HYDROXYPENTANOATE
• Synonyms: (S)-METHYL 4-(TERT-BUTOXYCARBONYLAMINO)-5-HYDROXYPENTANOATE;(S)-4-[[(tert-Butoxy)carbonyl]amino]-5-hydroxypentanoic acid methyl ester
• CAS NO: 126587-35-7
• Molecular Formula: C₁₁H₂₁NO₅
• Molecular Weight: 247.29
• Mol File: 126587-35-7.mol

Chemical Properties

• Melting Point: 40.5-41.5 °C
• Boiling Point: 374.918 °C at 760 mmHg
• Flash Point: 180.544 °C
• Appearance: /
• Density: 1.104
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.463
• PKA: 11.76±0.46(Predicted)
• CAS DataBase Reference: (S)-METHYL 4-(TERT-BUTOXYCARBONYLAMINO)-5-HYDROXYPENTANOATE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-METHYL 4-(TERT-BUTOXYCARBONYLAMINO)-5-HYDROXYPENTANOATE(126587-35-7)
• EPA Substance Registry System: (S)-METHYL 4-(TERT-BUTOXYCARBONYLAMINO)-5-HYDROXYPENTANOATE(126587-35-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 126587-35-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
(S)-METHYL 4-(TERT-BUTOXYCARBONYLAMINO)-5-HYDROXYPENTANOATE is used as a key intermediate in the synthesis of pharmaceuticals for its ability to be incorporated into complex molecular structures. The presence of both ester and amino functionalities allows for a wide range of chemical reactions, facilitating the development of new drugs.
Used in Organic Chemistry:
In the field of organic chemistry, (S)-METHYL 4-(TERT-BUTOXYCARBONYLAMINO)-5-HYDROXYPENTANOATE is utilized as a valuable intermediate due to its capacity to participate in various organic transformations. The tert-butoxycarbonyl protecting group can be removed under mild conditions, enabling further chemical manipulations and the exposure of the amino function for additional reactions.
Used in Bioactive Molecule Synthesis:
(S)-METHYL 4-(TERT-BUTOXYCARBONYLAMINO)-5-HYDROXYPENTANOATE is also used as a precursor in the synthesis of bioactive molecules, where its unique structure and functional groups contribute to the creation of compounds with potential therapeutic or biological activity.

InChI:InChI=1/C11H21NO5/c1-11(2,3)17-10(15)12-8(7-13)5-6-9(14)16-4/h8,13H,5-7H2,1-4H3,(H,12,15)/t8-/m0/s1

Upstream product

• 45214-91-3 (2S)-2-[(tert-butoxy)carbonylamino]-4-(methoxycarbonyl)butanoic acid 
• 541-41-3 chloroformic acid ethyl ester 
• 59279-60-6 dimethyl (2S)-2-[(tert-butoxycarbonyl)amino]pentanedioate 
• 81658-26-6 tert-butyl (S)-2-(((tert-butyldimethylsilyl)oxy)methyl)-5-oxopyrrolidin-1-carboxylate 
• 96014-55-0 Methyl (4S)-4-(N-(tert-Butoxycarbonyl)amino)-5-((tert-butyldimethylsilyl)oxy)pentanoate 
• 3077-51-8 γ-methyl L-glutamate hydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1499-55-4 L-glutamic acid 5-methyl ester 
• 56-86-0 L-glutamic acid 
• 39538-20-0 (S)-2-tert-Butoxycarbonylamino-pentanedioic acid 1-(2,5-dioxo-pyrrolidin-1-yl) ester 5-methyl ester 

Downstream Products

• 1422740-22-4 C₃₃H₅₁NO₆Si 
• 1422740-23-5 C₂₈H₃₆N₂O₅ 
• 1422740-24-6 C₃₂H₃₈N₂O₅ 
• 1276112-33-4 C₃₂H₃₉NO₆ 
• 1276112-41-4 C₃₅H₄₃NO₅ 
• 1276112-34-5 C₃₅H₄₃NO₅ 
• 1422740-11-1 C₃₃H₅₁NO₆Si 
• 1333536-82-5 (4S)-4-N-tert-butoxycarbonylamino-5-(triphenylmethylthio)-pentanoic acid allyl ester 
• 1603835-90-0 (S)-N-(1-azidomethyl-4-O-tert-butyldiphenylsilyloxybutyl)-N-2-cyanoethyl diethylphosphonoacetamide 
• 1603835-87-5 (S)-4-amino-5-azido-O-tert-butyldiphenylsilyl-1-pentanol 
• 220623-07-4 (1S,2S,5R)-tert-butyl 3-aza-4-oxo-2-<(1,1,2,2-tetramethyl-1-silapropoxy)methyl>bicyclo<3.1.0>hexane-3-carboxylate 
• 293297-95-7 (5S)-N-(tert-Butoxycarbonyl)-5-(((tert-butyldimethylsilyl)oxy)methyl)-3-(phenylseleno)pyrrolidin-2-one 
• 81658-27-7 (S)-tert-butyl 2-(((tert-butyldimethylsilyl)oxy)methyl)-5-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate 
• 106191-02-0 (S)-5-((tert-butyldimethylsilyloxy)methyl)pyrrolidin-2-one 

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