1603885-68-2

Upstream product

• 164014-40-8 2,2-dimethyl-5-trifluoromethylsulfonyloxy-4H-(1,3)benzodioxin-4-one 
• 154714-19-9 5-hydroxy-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one 
• 81445-44-5 (S)-2-(benzyloxy)propanal 
• 100-39-0 benzyl bromide 
• 54783-72-1 ethyl (S)-2-(benzyloxy)propionate 
• 74-88-4 methyl iodide 
• 1603885-67-1 (R)-3-allyl-8-methoxyisochroman-1-one 
• 123484-13-9 (S)-((but-3-en-2-yloxy)methyl)benzene 
• 1603885-47-7 (R)-3-allyl-8-hydroxyisochroman-1-one 
• 303-07-1 2,6-Dihydroxybenzoic acid 
• 659738-79-1 (R)-5-(2-hydroxypent-4-enyl)-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one 
• 313644-65-4 2-(2,2-dimethyl-4-oxo-4H-benzo[d][1,3]dioxin-5-yl)acetaldehyde 
• 204846-40-2 2,2-dimethyl-5-(2-propenyl)-4H-1,3-benzodioxin-4-one 

Relevant academic research and scientific papers

First enantioselective total synthesis of penicimarin B, aspergillumarins A and B

A convergent enantioselective synthesis of penicimarin B, aspergillumarin A and B has been reported using Brown's allylation, DeBrabander-Bhattacharjee lactonization and Grubbs cross coupling metathesis. During this synthesis we have standardized the conditions for DeBrabande-Bhattacharjee lactonization to obtain excellent yield (>90%).