160447-11-0

Basic information

• Product Name: 4(S)-(1-methylethyl)-3-[1-oxo-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propyl]-2-oxazolidinone
• Synonyms: 4(S)-(1-methylethyl)-3-[1-oxo-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propyl]-2-oxazolidinone
• CAS NO: 160447-11-0
• Molecular Weight: 493.605
• Mol File: 160447-11-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4(S)-(1-methylethyl)-3-[1-oxo-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propyl]-2-oxazolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: 4(S)-(1-methylethyl)-3-[1-oxo-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propyl]-2-oxazolidinone(160447-11-0)
• EPA Substance Registry System: 4(S)-(1-methylethyl)-3-[1-oxo-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propyl]-2-oxazolidinone(160447-11-0)

Safety Data

• Hazardous Substances Data: 160447-11-0(Hazardous Substances Data)

Upstream product

• 17016-83-0 (4S)-4-isopropyl-1,3-oxazolidin-2-one 
• 76-83-5 trityl chloride 
• 102676-60-8 3-(1-triphenylmethyl-1H-imidazol-4-yl)propanoic acid methyl ester 
• 31434-93-2 methyl 3-(4-imidazolyl)propionate 
• 160446-35-5 3-(1H-1-triphenylmethylimidazol-4-yl)propanoic acid 

Downstream Products

• 220588-89-6 4(S),5(S)-bis[(tert-butyldimethylsilyl)oxy]-N-[1(S)-(cyclohexylmethyl)-2(R),3(S)-dihydroxy-5-methylhexyl]-6-phenyl-2(R)-[[1-(triphenylmethyl)-1H-imidazol-4-yl]methyl]hexanamide 
• 220588-90-9 N-[1(S)-(cyclohexylmethyl)-2(R),3(S)-dihydroxy-5-methylhexyl]-4(S),5(S)-dihydroxy-6-phenyl-2(R)-[[1-(triphenylmethyl)-1H-imidazol-4-yl]methyl]hexanamide 
• 220589-06-0 4,5-bis-(tert-butyl-dimethyl-silanyloxy)-6-phenyl-2-(1-trityl-1H-imidazol-4-ylmethyl)-hexanoic acid 
• 220588-88-5 5(S)-[1(S)-(benzoyloxy)-2-phenylethyl]-3(R)-[[1-(triphenylmethyl)-1H-imidazol-4-yl]methyl]dihydrofuran-2(3H)-one 
• 220588-87-4 5(RS)-[1(RS)-hydroxy-2-phenylethyl]-3(R)-[[1-(triphenylmethyl)-1H-imidazol-4-yl]methyl]dihydrofuran-2(3H)-one 
• 160447-15-4 N¹-(1-cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexyl)-N⁴-dimethylcarbamoylmethyl-N⁴-(1-phenyl-ethyl)-2-(1-trityl-1H-imidazol-4-ylmethyl)-succinamide 
• 160447-13-2 N-<1(S)-(cyclohexylmethyl)-2(R),3(S)-dihydroxy-5-methylhexyl>-4-oxo-4-(phenylmethoxy)-2(R)-<<(1-triphenylmethyl)-1H-imidazol-4-yl>methyl>butanamide 
• 160447-21-2 (R)-N-((1S,2R,3S)-1-Cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexyl)-3-(1-trityl-1H-imidazol-4-ylmethyl)-succinamic acid 
• 160447-14-3 2-(1-trityl-1H-imidazol-4-ylmethyl)-succinic acid 4-benzyl ester 
• 160447-12-1 3-<1,4-dioxo-4-(phenylmethoxy)-2(S)-<(1-triphenylmethyl-1H-imidazol-4-yl)methyl>butyl>-4(S)-(1-methylethyl)-2-oxazolidinone 

Relevant articles and documents

Novel small renin inhibitors containing 4,5- or 3,5-Dihydroxy-2-substituted-6-phenylhexanamide replacements at the P2-P3 sites

Renin inhibitors containing a 4,5- or a 3,5-dihydroxy-2-substituted-6-phenylhexanamide fragment at the P2-P3 sites have been prepared and evaluated. The four possible diastereomeric diols of the two series of inhibitors were synthesi