1606131-67-2Relevant academic research and scientific papers
Sequential C3 and C5 Direct C-H Arylation of Imidazo[1,2-a]pyrazines with (Hetero)aryl Bromides
Johnson, Brett M.,Huestis, Malcolm P.
supporting information, p. 1589 - 1593 (2015/10/05)
An efficient reaction manifold for the preparation of C3/C5-diarylimidazo[1,2-a]pyrazines through sequential C3 and C5 direct arylation is disclosed. The two distinct palladium catalyst systems showcased herein are compatible with a wide variety of aryl and heteroaryl bromides and are also operative in a one-pot, twofold C-H functionalization event. An efficient reaction manifold for the preparation of C3/C5-diarylimidazo[1,2-a]pyrazines through sequential C3 and C5 direct arylation is disclosed. The two distinct palladium catalyst systems showcased herein are compatible with a wide variety of aryl and heteroaryl bromides and are also operative in a one-pot, twofold C-H functionalization event.
Sequential C3 and C5 direct C-H arylation of imidazo[1,2-a]pyrazines with (Hetero)aryl bromides
Johnson, Brett M.,Huestis, Malcolm P.
, p. 1589 - 1593 (2014/03/21)
An efficient reaction manifold for the preparation of C3/C5- diarylimidazo[1,2-a]pyrazines through sequential C3 and C5 direct arylation is disclosed. The two distinct palladium catalyst systems showcased herein are compatible with a wide variety of aryl and heteroaryl bromides and are also operative in a one-pot, twofold C-H functionalization event. Copyright
