1606159-04-9

Basic information

• Product Name: C₁₅H₁₁N₃O₃S
• CAS NO: 1606159-04-9
• Molecular Weight: 313.337
• Mol File: 1606159-04-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₅H₁₁N₃O₃S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₅H₁₁N₃O₃S(1606159-04-9)
• EPA Substance Registry System: C₁₅H₁₁N₃O₃S(1606159-04-9)

Safety Data

• Hazardous Substances Data: 1606159-04-9(Hazardous Substances Data)

Upstream product

• 619-17-0 4-Nitroanthranilic acid 
• 99-55-8 2-methyl-5-nitroaniline 
• 951-97-3 2-acetamido-4-nitrobenzoic acid 
• 2879-79-0 N-(2-methyl-5-nitrophenyl)acetamide 
• 66365-41-1 triphenylphosphine-thiocyanogen 
• 100-52-7 benzaldehyde 
• 186804-40-0 C₁₄H₁₀N₂O₄ 

Downstream Products

• 1606159-98-1 C₁₉H₁₈N₄O₄ 

Relevant articles and documents

Functionalization of quinazolin-4-ones part 1: Synthesis of novel 7-substituted-2-thioxo quinazolin-4-ones from 4-substituted-2-aminobenzoic acids and PPh3(SCN)2

4-(Nitro, amino, acetylamino)-2-aminobenzoic acid were allowed to react with PPh3(SCN)2 and gave the crossholding 7-nitro, 7-acetylamino- and 7-amino-2-thioxo quinazolin-4-ones respectively. The nature of the substituent at position 4 of the 2-aminobenzoic acids has significant influence on the outcome of the cyclisation reaction with PPh 3(SCN)2. Similarly, the nature of the substituent at position 7 of the 2-substituted quinazolin-4-ones significantly affected the ease with which alkylation reactions could be performed. The alkylation selectivity of the 7- substiuted-2-thioxo quinazolin-4-ones was found to depend on the nature of the alkyl halide and the nature of the substituent at position 2.