16069-16-2

Basic information

• Product Name: N-acryloylphenylalanine
• CAS NO: 16069-16-2
• Molecular Formula: C₁₂H₁₃NO₃
• Molecular Weight: 219.2365
• Mol File: 16069-16-2.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 465.8°C at 760 mmHg
• Flash Point: 235.5°C
• Density: 1.189g/cm³
• Vapor Pressure: 1.78E-09mmHg at 25°C
• Refractive Index: 1.555
• CAS DataBase Reference: N-acryloylphenylalanine(CAS DataBase Reference)
• NIST Chemistry Reference: N-acryloylphenylalanine(16069-16-2)
• EPA Substance Registry System: N-acryloylphenylalanine(16069-16-2)

Safety Data

• Hazardous Substances Data: 16069-16-2(Hazardous Substances Data)

Upstream product

• 63-91-2 L-phenylalanine 
• 814-68-6 acryloyl chloride 

Downstream Products

• 1358017-45-4 (S)-N-(1-oxo-3-phenyl-1-(prop-2-yn-1-ylamino)propan-2-yl)acrylamide 
• 1223582-21-5 (S)-N-acryloylphenylalanine-4-styrybenzyl ester 
• 18939-41-8 (S)-methyl-2-acrylamido-3-phenylpropanoate 

Relevant articles and documents

Microwave-assisted graft copolymerization of amino acid based monomers onto starch and their use as drug carriers

This paper describes the synthesis of two amino acid-based monomer and their graft copolymerization onto starch and utilization of the prepared graft copolymers as drug carriers. The two monomers were synthesized and reacted with acryloyl chloride to get

Models for Use of α-Amino Acids as Chiral Auxiliaries in Asymmetric Diels-Alder Reactions

Three different models, depending on the Lewis acid used as a catalyst and the α-amino acid used as a chiral auxiliary, account for the diastereofacial selectivity obtained in reactions of cyclopentadiene with N-acryloyl derivatives of L-proline, L-phenylalanine, L-alanine, and N-methyl-L-alanine esters.For α-amino acids without an NH group and aluminum catalysts, a reactive conformer with antiplanar enoate conformation similar to those postulated for acrylates with only one center capable of coordination is proposed.These dienophiles form a chelate complex, where the acryloyl moiety is in syn conformation, with TiCl4.For α-amino acids with an NH group, a reactive intermediate with an antiplanar disposition in the acryloyl moiety and the conformation of the amino ester fixed by an intramolecular hydrogen bond accounts for the results with both kinds of catalyst.These models seem to have general application for the use of α-amino acids as chiral auxiliaries in asymmetric Diels-Alder reactions.

Metal-Free Polymer-Based Affinity Medium for Selective Purification of His6-Tagged Proteins

We report a metal free synthetic hydrogel copolymer with affinity and selectivity for His6-tagged peptides and proteins. Small libraries of copolymers incorporating charged and hydrophobic functional groups were screened by an iterative process for His6 p

Anti-tumor composition carrying vincaleukoblastinum and preparation method thereof

The invention relates to an anti-tumor composition carrying vincaleukoblastinum. The composition is characterized in that the periphery of a vincaleukoblastinum molecule is wrapped with two bi-functional monomers through hydrogen bond connection, positive