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2,4,5-Trimethylphenylmagnesium bromide is an organometallic compound that serves as a reagent in organic synthesis, specifically for introducing the 2,4,5-trimethylphenyl group into organic molecules. It is prepared from 2,4,5-trimethylphenyl bromide and magnesium metal in the presence of a solvent such as diethyl ether or tetrahydrofuran. This highly reactive species is capable of undergoing nucleophilic addition reactions with various electrophiles, facilitating the formation of new carbon-carbon or carbon-heteroatom bonds.

160727-03-7

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160727-03-7 Usage

Uses

Used in Pharmaceutical Industry:
2,4,5-Trimethylphenylmagnesium bromide is used as a synthetic reagent for the synthesis of complex organic molecules, which are essential in the development of pharmaceutical compounds. Its ability to form new carbon-carbon or carbon-heteroatom bonds makes it a valuable tool in creating diverse drug molecules with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 2,4,5-Trimethylphenylmagnesium bromide is employed as a synthetic reagent for the production of complex organic molecules that are used in the formulation of agrochemicals. Its reactivity in nucleophilic addition reactions allows for the creation of molecules with specific properties, such as pest control or crop protection, that are crucial for agricultural productivity and sustainability.

Check Digit Verification of cas no

The CAS Registry Mumber 160727-03-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,0,7,2 and 7 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 160727-03:
(8*1)+(7*6)+(6*0)+(5*7)+(4*2)+(3*7)+(2*0)+(1*3)=117
117 % 10 = 7
So 160727-03-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H11.BrH.Mg/c1-7-4-5-8(2)9(3)6-7;;/h5-6H,1-3H3;1H;/q;;+1/p-1/rC9H11BrMg/c1-6-4-8(3)9(11-10)5-7(6)2/h4-5H,1-3H3

160727-03-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name magnesium,1,2,4-trimethylbenzene-5-ide,bromide

1.2 Other means of identification

Product number -
Other names 2,4,5-Trimethylphenylmagnesium bromide 0.5 M in Tetrahydrofuran

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:160727-03-7 SDS

160727-03-7Relevant academic research and scientific papers

Cyclotrimerisation of isocyanates catalysed by low-coordinate Mn(ii) and Fe(ii) m-terphenyl complexes

Sharpe, Helen R.,Geer, Ana M.,Williams, Huw E. L.,Blundell, Toby J.,Lewis, William,Blake, Alexander J.,Kays, Deborah L.

, p. 937 - 940 (2017)

Two- and three-coordinate m-terphenyl complexes of manganese and iron are efficient catalysts for the selective cyclotrimerisation of primary aliphatic isocyanates affording isocyanurates in short reaction times and under mild conditions.

Copper-catalyzed difluoromethylation of β,γ-unsaturated carboxylic acids: An efficient allylic difluoromethylation

He, Zhengbiao,Hu, Mingyou,Luo, Tao,Li, Lingchun,Hu, Jinbo

supporting information, p. 11545 - 11547 (2013/01/15)

Not one but two! A new strategy for the regiospecific construction of compounds with allylic CF2H groups has been developed. The decarboxylative (phenylsulfonyl)difluoromethylation of β,γ- unsaturated carboxylic acids is catalyzed by a Lewis acid (CuCl 2·2 H2O), and the resulting product easily undergoes desulfonylation. Copyright

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