160730-15-4Relevant academic research and scientific papers
Total synthesis of a frog poison, (±)-epibatidine, a potent non-opioid analgesic
Okabe,Natsume
, p. 1432 - 1436 (1994)
A non-opioid analgesic, epibatidine (1), isolated from Ecuadoran poison frogs was synthesized in the racemic form starting from a readily available compound 2. A partial Curtius rearrangement product 5 of 2 was converted into 12c by way of the ketone 3 an
