16075-92-6

Basic information

• Product Name: 6-phenyl-3-thioxo-3,4-dihydro-1,2,4-triazin-5(2H)-one
• Synonyms: 1,2,4-triazin-5(2H)-one, 3,4-dihydro-6-phenyl-3-thioxo-; 1,2,4-triazin-5-ol, 3-mercapto-6-phenyl-
• CAS NO: 16075-92-6
• Molecular Formula: C₉H₇N₃OS
• Molecular Weight: 205.2364
• Mol File: 16075-92-6.mol
• Article Data: 6

Chemical Properties

• Density: 1.46g/cm³
• Refractive Index: 1.732
• CAS DataBase Reference: 6-phenyl-3-thioxo-3,4-dihydro-1,2,4-triazin-5(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-phenyl-3-thioxo-3,4-dihydro-1,2,4-triazin-5(2H)-one(16075-92-6)
• EPA Substance Registry System: 6-phenyl-3-thioxo-3,4-dihydro-1,2,4-triazin-5(2H)-one(16075-92-6)

Safety Data

• Hazardous Substances Data: 16075-92-6(Hazardous Substances Data)

Upstream product

• 100-42-5 styrene 
• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 79-19-6 thiosemicarbazide 
• 106119-76-0 4-Nitroso-6-phenyl-3-thioxo-2,3,4,5-tetrahydro-1,2,4-triazin-5-one 
• 611-73-4 Benzoylformic acid 
• 97099-91-7 3-(1-Methyl-prop-2-ynylsulfanyl)-6-phenyl-2H-[1,2,4]triazin-5-one 
• 97099-89-3 6-Phenyl-3-prop-2-ynylsulfanyl-2H-[1,2,4]triazin-5-one 
• 18465-40-2 phenylglyoxalic acid thiosemicarbazone 
• 108106-80-5 5-amino-6-phenyl-2H-[1,2,4]triazine-3-thione 
• 10050-86-9 (4-dimethylamino-phenylimino)-phenyl-acetonitrile 

Downstream Products

• 22278-82-6 4-amino-6-phenyl-5-oxo-3-thioxo-2,3,4,5-tetrahydro<1,2,4>triazine 
• 115482-57-0 3-(2,4-Dinitrophenylthio)-4,5-dihydro-6-phenyl-1,2,4-triazin-5-(4H)-one 
• 53047-90-8 2-(4-methoxy-benzylidene)-6-phenyl-thiazolo[3,2-b][1,2,4]triazine-3,7-dione 
• 53047-89-5 2-benzylidene-6-phenyl-thiazolo[3,2-b][1,2,4]triazine-3,7-dione 
• 53047-91-9 2-(4-nitro-benzylidene)-6-phenyl-thiazolo[3,2-b][1,2,4]triazine-3,7-dione 
• 53047-92-0 2-(4-chloro-benzylidene)-6-phenyl-thiazolo[3,2-b][1,2,4]triazine-3,7-dione 
• 60438-35-9 4-morpholin-4-ylmethyl-6-phenyl-3-thioxo-3,4-dihydro-2H-[1,2,4]triazin-5-one 
• 118726-95-7 (5-oxo-6-phenyl-4,5-dihydro-[1,2,4]triazin-3-ylmercapto)-acetic acid 
• 23891-08-9 5-phenyl-6-azauracil 

Relevant articles and documents

Two regioisomers of condensed thio-heterocyclic triazine synthesized from 6-phenyl-3-thioxo-2,3,4,5-tetra-hydro-1,2,4-triazin-5-one

In the crystal structure of 6-phenyl-3-thioxo-2,3,4,5-tetra-hydro-1,2,4- triazin-5-one, C9H7N3OS, (I), the 1,2,4-triazine moieties are connected by face-to-face contacts through two kinds of double hydrogen bonds (N - H...

Synthesis and biological evaluation of 3,6-diaryl-7H-thiazolo[3,2-b] [1,2,4]triazin-7-one derivatives as acetylcholinesterase inhibitors

Acetylcholinesterase (AChE) inhibitors played an important role in developing a cure for Alzheimer' s disease. In order to study on the influence of modifications at different groups and side chains on the AChE inhibitory ability and the active sites of 7

PALLADIUM-CATALYZED CYCLIZATION REACTIONS. UNICQUE SYNTHESIS OF CONDENSED THIAZOLES

The facile synthesis of 3-methylene-2,3-dihydro-5H-thiazolopyrimidin-5-ones (9) has been performed by the catalytic action of a Pd(II) salt on 4-propargylthiopyrimidin-2(1H)-ones (6).Similar Pd(II)-catalyzed cyclization of 3-propargylthio-1,2,4-triazin-5(2H)-ones (10) gives 6-methylene-6,7-dihydro-4H-thiazolotriazin-4-ones (11) as a main product. 3-methylene-2,3-dihydro-7H-thiazolotriazin-7-ones (12), the regioisomers of 11, are provided by a base-catalyzed cyclization of 10.