16075-92-6

Upstream product

• 100-42-5 styrene 
• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 79-19-6 thiosemicarbazide 
• 10050-86-9 (4-dimethylamino-phenylimino)-phenyl-acetonitrile 
• 106119-76-0 4-Nitroso-6-phenyl-3-thioxo-2,3,4,5-tetrahydro-1,2,4-triazin-5-one 
• 611-73-4 Benzoylformic acid 
• 97099-91-7 3-(1-Methyl-prop-2-ynylsulfanyl)-6-phenyl-2H-[1,2,4]triazin-5-one 
• 97099-89-3 6-Phenyl-3-prop-2-ynylsulfanyl-2H-[1,2,4]triazin-5-one 
• 18465-40-2 phenylglyoxalic acid thiosemicarbazone 
• 108106-80-5 5-amino-6-phenyl-2H-[1,2,4]triazine-3-thione 

Downstream Products

• 23891-08-9 5-phenyl-6-azauracil 
• 118726-95-7 (5-oxo-6-phenyl-4,5-dihydro-[1,2,4]triazin-3-ylmercapto)-acetic acid 
• 115482-57-0 3-(2,4-Dinitrophenylthio)-4,5-dihydro-6-phenyl-1,2,4-triazin-5-(4H)-one 
• 22278-82-6 4-amino-6-phenyl-5-oxo-3-thioxo-2,3,4,5-tetrahydro<1,2,4>triazine 
• 53047-90-8 2-(4-methoxy-benzylidene)-6-phenyl-thiazolo[3,2-b][1,2,4]triazine-3,7-dione 
• 53047-89-5 2-benzylidene-6-phenyl-thiazolo[3,2-b][1,2,4]triazine-3,7-dione 
• 53047-91-9 2-(4-nitro-benzylidene)-6-phenyl-thiazolo[3,2-b][1,2,4]triazine-3,7-dione 
• 53047-92-0 2-(4-chloro-benzylidene)-6-phenyl-thiazolo[3,2-b][1,2,4]triazine-3,7-dione 
• 60438-35-9 4-morpholin-4-ylmethyl-6-phenyl-3-thioxo-3,4-dihydro-2H-[1,2,4]triazin-5-one 

Relevant academic research and scientific papers

Two regioisomers of condensed thio-heterocyclic triazine synthesized from 6-phenyl-3-thioxo-2,3,4,5-tetra-hydro-1,2,4-triazin-5-one

In the crystal structure of 6-phenyl-3-thioxo-2,3,4,5-tetra-hydro-1,2,4- triazin-5-one, C9H7N3OS, (I), the 1,2,4-triazine moieties are connected by face-to-face contacts through two kinds of double hydrogen bonds (N - H...

Reactions of 4-nitroso-1,2,4-triazine with derivatives of hydrazine

The action of hydrazine on 4-nitroso-6-phenyl-1,2,4-triazine-3(2H)-thione-5-one results in the cleavage of the nitroso group. The action of phenylhydrazine results in the reduction of the double bond in the triazine ring together with the cleavage of the

Synthesis and biological evaluation of 3,6-diaryl-7H-thiazolo[3,2-b] [1,2,4]triazin-7-one derivatives as acetylcholinesterase inhibitors

Acetylcholinesterase (AChE) inhibitors played an important role in developing a cure for Alzheimer' s disease. In order to study on the influence of modifications at different groups and side chains on the AChE inhibitory ability and the active sites of 7

Chemotherapeutic agents: Part XXVI - Synthesis and evaluation of π-deficient symmetrical and unsymmetrical triazines as antimalarials

1,2,4-Triazine derivatives (3-6) have been prepared by the electrophilic substitution on 2.Symmetrical triazines 8 and 11 have been obtained by nucleophilic reaction of dicyandiamide with nitriles 7 and 9.

PALLADIUM-CATALYZED CYCLIZATION REACTIONS. UNICQUE SYNTHESIS OF CONDENSED THIAZOLES

The facile synthesis of 3-methylene-2,3-dihydro-5H-thiazolopyrimidin-5-ones (9) has been performed by the catalytic action of a Pd(II) salt on 4-propargylthiopyrimidin-2(1H)-ones (6).Similar Pd(II)-catalyzed cyclization of 3-propargylthio-1,2,4-triazin-5(2H)-ones (10) gives 6-methylene-6,7-dihydro-4H-thiazolotriazin-4-ones (11) as a main product. 3-methylene-2,3-dihydro-7H-thiazolotriazin-7-ones (12), the regioisomers of 11, are provided by a base-catalyzed cyclization of 10.

PALLADIUM-CATALYZED CYCLIZATION REACTIONS OF 3-PROPARGYLTHIO-1,2,4-TRIAZIN-5(2H)-ONES TO THIAZOLO-1,2,4-TRIAZINONES

Selective transformation of 3-propargylthio-1,2,4-triazin-5(2H)-ones (1) to 6-methylene-6,7-dihydro-4H-thiazolo- triazin-4-ones (2) and 3-methylene-2,3-dihydro-7H-thiazolotriazin-7-ones (3) is performed under the conditions of Pd(II) salt or sodium hydroxide catalysis, respectively.