16078-63-0 Usage
Description
Ethyl 3-amino-1-phenyl-1H-pyrazole-4-carboxylate is a pyrazole derivative with the molecular formula C13H13N3O2. It features a five-membered heterocyclic ring with two nitrogen atoms, a phenyl group attached to the pyrazole ring, and an ethyl ester group attached to the carboxylate functional group. ethyl 3-aMino-1-phenyl-1H-pyrazole-4-carboxylate has potential applications in medicinal chemistry due to its interesting structural and pharmacological properties, including anti-inflammatory, antiviral, and anticancer activities.
Uses
Used in Medicinal Chemistry:
Ethyl 3-amino-1-phenyl-1H-pyrazole-4-carboxylate is used as a chemical compound in medicinal chemistry for its potential pharmacological activities. Its pyrazole structure and functional groups contribute to its diverse applications in the development of new drugs.
Used in Anti-inflammatory Applications:
Ethyl 3-amino-1-phenyl-1H-pyrazole-4-carboxylate is used as an anti-inflammatory agent due to its ability to modulate inflammatory pathways and reduce inflammation-related symptoms.
Used in Antiviral Applications:
Ethyl 3-amino-1-phenyl-1H-pyrazole-4-carboxylate is used as an antiviral agent, potentially inhibiting viral replication and reducing the severity of viral infections.
Used in Anticancer Applications:
Ethyl 3-amino-1-phenyl-1H-pyrazole-4-carboxylate is used as an anticancer agent, exhibiting potential inhibitory effects on tumor growth and progression. Its pyrazole structure and functional groups may contribute to its activity against various types of cancer.
Used in Drug Development:
Ethyl 3-amino-1-phenyl-1H-pyrazole-4-carboxylate is used in drug development as a promising candidate for the synthesis of new pharmaceutical compounds with potential therapeutic benefits in various diseases and conditions. Its unique structure and pharmacological properties make it an interesting target for further research and exploration.
Check Digit Verification of cas no
The CAS Registry Mumber 16078-63-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,0,7 and 8 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 16078-63:
(7*1)+(6*6)+(5*0)+(4*7)+(3*8)+(2*6)+(1*3)=110
110 % 10 = 0
So 16078-63-0 is a valid CAS Registry Number.
16078-63-0Relevant articles and documents
HETERO-HALO INHIBITORS OF HISTONE DEACETYLASE
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Paragraph 207, (2017/01/26)
This invention provides compounds that are inhibitors of HDAC2. The compounds (e.g., compounds according to Formula I, II or any of Compounds 100-128 or any of those in Tables 2 or 3) accordingly are useful for treating, alleviating, or preventing a condition in a subject such as a neurological disorder, memory or cognitive function disorder or impairment, extinction learning disorder, fungal disease or infection, inflammatory disease, hematological disease, or neoplastic disease, or for improving memory or treating, alleviating, or preventing memory loss or impairment.
Application of Ullmann and Ullmann-Finkelstein reactions for the synthesis of N-aryl-N-(1H-pyrazol-3-yl) acetamide or N-(1-aryl-1H-pyrazol-3-yl) acetamide derivatives and pharmacological evaluation
Deprez-Poulain, Rebecca,Cousaert, Nicolas,Toto, Patrick,Willand, Nicolas,Deprez, Benoit
scheme or table, p. 3867 - 3876 (2011/11/12)
Ullmann-type reactions are becoming a major tool in medicinal chemistry. In this article, we describe the use of these Copper-catalyzed reactions with various precursors, acyl-heteroarylamines or pyrazoles of interest for pharmacomodulation. To the medicinal chemist they offer new, usually untapped disconnection approaches to compounds of interest. They thus open the way to new original analogues of bioactive compounds possibly not patented, from common building-blocks. They also allow C to N bioisosteric replacements, which sometimes are synthetically challenging. We report for the first time the critical effect of acetylamino substituents on the regioselective arylation of unsymmetrical pyrazoles that are useful for medicinal chemists. Finally, we have applied this strategy to the design of novel AT1 receptor antagonists. Though this family has been extensively investigated in the past 30 years, N-arylation and C to N replacement made possible by Ullmann chemistry, can produce original antagonists.
Heterocyclic system. XI. Synthesis of 1H,4H-pyrazolo[4,3-b]pyrrolizine and 2H,4H-pyrazolo[4,3-b]pyrrolizine derivatives
Massa,Mai,Artico,Corelli
, p. 1805 - 1808 (2007/10/02)
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