1608-47-5

Basic information

• Product Name: 3,4-DIIODOTOLUENE
• Synonyms: 3,4-DIIODOTOLUENE
• CAS NO: 1608-47-5
• Molecular Formula: C₇H₆I₂
• Molecular Weight: 343.93
• Product Categories: Iodine Compounds
• Mol File: 1608-47-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 279.9°C at 760 mmHg
• Flash Point: 133.7°C
• Appearance: /
• Density: 2.295g/cm³
• Vapor Pressure: 0.00663mmHg at 25°C
• Refractive Index: 1.684
• CAS DataBase Reference: 3,4-DIIODOTOLUENE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-DIIODOTOLUENE(1608-47-5)
• EPA Substance Registry System: 3,4-DIIODOTOLUENE(1608-47-5)

Safety Data

• Hazardous Substances Data: 1608-47-5(Hazardous Substances Data)

Usage

General Description

3,4-Diiodotoluene is a chemical compound with the molecular formula C7H6I2. It is a derivative of toluene, a common organic solvent and precursor to many chemical compounds. 3,4-Diiodotoluene is used as an intermediate in the synthesis of pharmaceuticals, dyes, and other organic compounds. It is a white crystalline solid with a strong odor and has a melting point of around 51-52°C. 3,4-Diiodotoluene is primarily used in the production of iodinated contrast media, which are used in medical imaging procedures such as CT scans and X-rays. It is also a useful reagent in organic synthesis and can be found in research laboratories and chemical manufacturing facilities. Overall, 3,4-Diiodotoluene is an important chemical compound with a variety of applications in industry and research.

InChI:InChI=1/C7H6I2/c1-5-2-3-6(8)7(9)4-5/h2-4H,1H3

Upstream product

• 13194-69-9 2-iodo-5-methylaniline 
• 2941-78-8 2-Amino-5-methylbenzoic acid 
• 624-31-7 4-tolyl iodide 
• 139778-27-1 2-Iodo-5-methylbenzenesulfonic acid 
• 104-15-4 toluene-4-sulfonic acid 
• 262373-15-9 4-methyl-2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 89-62-3 4-methyl-2-nitroaniline 
• 5326-39-6 4-iodo-3-nitrotoluene 

Downstream Products

• 165544-43-4 3-Methyl-1,2-bis(phenylethynyl)benzene 
• 40314-06-5 5-methyl-1H-isoindole-1,3-(2H)-dione 
• 85090-26-2 5-methyl-2-phenylisoindoline-1,3-dione 

Relevant articles and documents

Aryne Insertion into I-I σ-Bonds

A new protocol for the efficient synthesis of o-diiodoarenes has been developed. This method allows the synthesis of substituted and polycyclic o-diiodoarenes, which are difficult to obtain by classical methods. This diiodination process involves the formal insertion of arynes into the I-I σ-bond.

Preparation of N-Substituted Phthalimides by Palladium-Catalyzed Carbonylation and Coupling of o-Dihalo Aromatics and Primary Amines

A novel method for the formation of N-substituted phthalimides is described which is based on the palladium-catalyzed carbonylation and coupling of o-dihalo aromatics and primary amines.Optimal conditions established for the reaction using o-diiodobenzene and aniline were DMAc (0.2 M), 115 deg C, 90 psi of CO, 3 percent PdCl2L2, and 2.4 equiv of DBU.This process is tolerant of a wide variety of functional groups and gives good yields of the desired products.Variables such as temperature, catalyst type and loading, CO pressure, solvent, and base were examined to optimize this reaction.The reaction of aniline with 1,2-dibromocyclopentene under similar conditions gave a variety of products.