16082-13-6 Usage
Uses
Used in Pharmaceutical Industry:
PYRIDAZINE-3,4-DICARBOXYLIC ACID DIETHYL ESTER is used as a key intermediate in the synthesis of drugs for the treatment of cardiovascular diseases. Its unique chemical structure allows for the development of compounds that can target specific pathways and receptors involved in these conditions, contributing to the creation of more effective and safer medications.
Used in Agrochemical Industry:
In the agrochemical sector, PYRIDAZINE-3,4-DICARBOXYLIC ACID DIETHYL ESTER is utilized as an intermediate in the production of various agrochemicals. Its properties enable the synthesis of compounds that can be used in the development of pesticides, herbicides, and other agricultural products, helping to improve crop yields and protect plants from pests and diseases.
Used in Chemical Research:
PYRIDAZINE-3,4-DICARBOXYLIC ACID DIETHYL ESTER is employed as a valuable research tool in chemical research. Its reactivity and functional groups make it suitable for exploring new synthetic pathways, developing novel compounds, and understanding the fundamental principles of organic chemistry.
Used in Material Science:
PYRIDAZINE-3,4-DICARBOXYLIC ACID DIETHYL ESTER is also used in the development of new materials, such as polymers, dyes, and other specialty chemicals. Its unique properties and versatility in reactions allow for the creation of innovative materials with specific characteristics and applications in various industries.
Safety Precautions:
Due to its potential irritant properties, PYRIDAZINE-3,4-DICARBOXYLIC ACID DIETHYL ESTER should be handled with care. It is essential to follow proper safety protocols, including wearing appropriate personal protective equipment and storing the compound in a cool, dry place away from sources of ignition to prevent any accidents or adverse reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 16082-13-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,0,8 and 2 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 16082-13:
(7*1)+(6*6)+(5*0)+(4*8)+(3*2)+(2*1)+(1*3)=86
86 % 10 = 6
So 16082-13-6 is a valid CAS Registry Number.
16082-13-6Relevant academic research and scientific papers
HIV INTEGRASE INHIBITORS
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Page 67, (2010/02/09)
The present invention concerns the compounds having the formula (1), N-oxides, salts, stereoisomeric forms, racemic mixtures, prodrugs, esters and metabolites thereof wherein (a) or (b); A, together with the two carbons of the phenyl ring to which it is attached forms a monocyclic aryl or a monocyclic Het2 ; R1 is hydrogen, halo, nitro, cyano, sultam, sulltim, C3-7cycloalkyl, C(=O)-R5, S(=O)y-R6, OR 7, NR8R9, C(=NR8)-R5, optionally polysubstituted C1-6alkyl, optionally polysubstituted C2-6alkenyl or optionally polysubstituted C2-6alkynyl; R 2 is hydrogen, C3-7cycloalkyl, aryl, Het1, Het2, C(=O)-R5, S(=O)Y-R6 OR7, NR8R9, C=NR8)-R5, or optionally polysubstituted C1-6alkyl, optionally polysubstituted C2-6alkenyl or optionally polysubstituted C2-6alkynyl. It further relates to their use as HIV integrase inhibitors, processes for their preparation as well as pharmaceutical compositions and diagnostic kits comprising them. It also concerns combinations thereof with other anti-retroviral agents, and to their use in assays as reference compounds or as reagents.
A Convenient Synthesis of Pyridazine-3,4-dicarboxylic Acid by a Hetero Diels-Alder Reaction
Vors, Jean-Pierre
, p. 579 - 582 (2007/10/02)
A convenient route to prepare unsubstituted pyridazine-3,4-dicarboxylic acid on a preparative scale is described.The synthesis involves a hetero Diels-Alder reaction between a new 1,2-diaza-1,3-diene and ethyl vinyl ether and oxidation of the intermediate 1,4,5,6-tetrahydropyridazine as the key step.
