16085-62-4

Basic information

• Product Name: 2-Pyridinecarboxaldehyde, (4-phenyl-2-thiazolyl)hydrazone
• CAS NO: 16085-62-4
• Molecular Formula: C15H12N4S
• Molecular Weight: 280.353
• Mol File: 16085-62-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-Pyridinecarboxaldehyde, (4-phenyl-2-thiazolyl)hydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinecarboxaldehyde, (4-phenyl-2-thiazolyl)hydrazone(16085-62-4)
• EPA Substance Registry System: 2-Pyridinecarboxaldehyde, (4-phenyl-2-thiazolyl)hydrazone(16085-62-4)

Safety Data

• Hazardous Substances Data: 16085-62-4(Hazardous Substances Data)

Upstream product

• 1121-60-4 pyridine-2-carbaldehyde 
• 3608-75-1 pyridine-2-carbaldehyde thiosemicarbazone 
• 70-11-1 α-bromoacetophenone 
• 34176-52-8 2-hydrazino-4-phenylthiazole 

Downstream Products

• 1632303-82-2 5-phenyl-3-(pyridin-2-yl)thiazolo[2,3-c][1,2,4]triazole 

Relevant articles and documents

Structural, antioxidant, antiproliferative and in?silico study of pyridine-based hydrazonyl?selenazoles and their sulphur isosteres

To evaluate the impact of chalcogen atom type, we performed a comparative study of antioxidant capacity and antiproliferative activity of a focused library of three pyridine-based hydrazonyl-1,3-selenazoles and their sulfur isosteres in five antioxidant assays and in six human solid tumor cell lines, respectively. In-silico calculations were further used to check pharmacokinetic profiles of investigated compounds such as drug-likeness parameters and interaction with water. Generally, selenium compounds appear to be more potent in comparison to sulfur isosteres in the performed essays.

Study of in vitro biological activity of thiazoles on Leishmania (Leishmania) infantum

Objectives: In the prospection of possible agents against neglected diseases, thiazole compounds are presented as promising candidates and are known to have activity against trypanosomatid parasites. Thus, this work aimed to evaluate the effects of thiazo

Study of oxidative cyclization using PhI(OAc)2 in the formation of benzo[4,5]thiazolo[2,3- C ][1,2,4]triazoles and related heterocycles - Scope and limitations

A one-pot, two-step reaction for the synthesis of benzo[4,5]thiazolo[2,3-c] [1,2,4]triazoles and related heterocycles under mild conditions was herein developed. The key step of this transformation is an oxidative cyclization employing PhI(OAc)2/sub