16089-71-7Relevant academic research and scientific papers
A facile and new method for the synthesis of α-aryl-N-methylnitrones in solvent-free media using silica gel-NaOH
Alavi Nikje,Bigdeli,Imanieh
, p. 1465 - 1468 (2004)
Substituted α-aryl-N-methylnitrones are prepared by the condensation reaction of N-methylhydroxylamine hydrochloride and benzaldehydes in solvent-free media using silica-gel-NaOH catalyst system. The yields are excellent regardless of the electron-donatin
Cucurbit[7]uril as a catalytic nanoreactor for one-pot synthesis of isoxazolidines in water
Floresta, Giuseppe,Gentile, Davide,Mineo, Placido G.,Nicosia, Angelo,Patamia, Vincenzo,Rescifina, Antonio
supporting information, p. 1194 - 1203 (2020/02/22)
The main objective of supramolecular chemistry is to mimic the macrosystems present in nature, a goal that fits perfectly with the green chemistry guidelines. The aim of our work is to use the hydrophobic cavity of cucurbit[7]uril (CB[7]) to mimic nature
A green synthesis of nitrones in glycerol
Shariatipour, Monire,Jadidinejad, Masoumeh,Heydari, Akbar
, (2019/11/11)
Abstract: An eco-friendly and efficient synthesis of nitrones is presented by condensation of an equimolar amount of aldehydes and N-substituted hydroxylamine hydrochlorides in glycerol as a recyclable solvent-catalyst. This novel protocol provides rapid and mild access to a series of nitrone derivatives in good to excellent yields in the absence of catalyst and base. Graphic abstract: SYNOPSIS In this study, a base-free protocol by using glycerol as the solvent-catalyst was applied for an eco-friendly synthesis of nitrones from the condensation of aldehydes and N-substituted hydroxylaminehydrochlorides.[Figure not available: see fulltext.].
Synthesis of 1,2,4-oxadiazolidines via [3+2] cycloaddition of nitrones with carbodiimides
Chen, Yuan,Fuyue, Liuting,Wang, Gangqiang,Wang, Hang,Lu, Chun,Guo, Haibing,St. Amant, Chiara,Sun, Shaofa,Xing, Yalan
supporting information, p. 4329 - 4332 (2019/03/19)
An efficient [3+2] cycloaddition of nitrones and carbodiimides has been developed. This 1,3-dipolar cycloaddition features high regioselectivity, mild and metal-free conditions, excellent functional group compatibility, and a broad substrate scope. The X-ray structures of two regio-isomers confirmed the regioselectivity of this transformation.
BPh3-Catalyzed [2+3] Cycloaddition of Ph3PCCO with Aldonitrones: Access to 5-Isoxazolidinones with Exocyclic Phosphonium Ylide Moieties
Brar, Amandeep,Unruh, Daniel K.,Ling, Natalie,Krempner, Clemens
, p. 6305 - 6309 (2019/08/20)
A method for the generation of 5-isoxazolidinones with exocyclic phosphonium ylide functionalities via [2+3] cycloaddition of Ph3PCCO and aldonitrones has been developed and applied in the synthesis of 4-alkylidene-5-isoxazolidinones via Wittig olefination. The reaction proceeds by BPh3 catalysis under mild conditions and with a broad substrate scope. A reaction pathway involving the activation of the aldonitrone via interactions with the Lewis acid BPh3 is proposed.
Accessing benzooxadiazepines: Via formal [4 + 3] cycloadditions of aza- o -quinone methides with nitrones
Zheng, Yong-Sheng,Tu, Liang,Gao, Li-Mei,Huang, Rong,Feng, Tao,Sun, Huan,Wang, Wen-Xuan,Li, Zheng-Hui,Liu, Ji-Kai
, p. 2639 - 2642 (2018/04/27)
An unprecedented and efficient [4 + 3] cycloaddition of N-(ortho-chloromethyl)aryl amides with nitrones has been developed. This approach provides easy access to a series of seven-membered benzooxadiazepine derivatives in good to excellent yields (up to 99% yield) under mild reaction conditions.
A highly diastereoselective [3+3] annulation reaction of aza-oxyallyl cations and nitrones
Chen, Rongxing,Sun, Shaofa,Wang, Gangqiang,Guo, Haibin
supporting information, p. 1916 - 1920 (2018/04/19)
An efficient synthesis of 1,2,4-oxadiazinan-5-ones via [3+3] cycloaddition of in situ generated aza-oxyallyl cations with nitrones has been developed. The protocol features easy operation, excellent yields, excellent diastereo-control, broad substrate sco
γ-Cyclodextrin as a Catalyst for the Synthesis of 2-Methyl-3,5-diarylisoxazolidines in Water
Floresta, Giuseppe,Talotta, Carmen,Gaeta, Carmine,De Rosa, Margherita,Chiacchio, Ugo,Neri, Placido,Rescifina, Antonio
, p. 4631 - 4639 (2017/05/12)
A green and efficient 1,3-dipolar cycloaddition of nitrones with different styrenes and cinnamates using a catalytic amount of γ-cyclodextrin (γ-CD) in water has been developed to give substituted isoxazolidines. γ-CD was found to be highly efficacious in
Crystal and molecular structure studies of (Z)-N-methyl-C-4-substituted phenyl nitrones by XRD, DFT, FTIR and NMR methods
Lasri, Jamal,Eltayeb, Naser Eltaher,Haukka, Matti,Alghamdi, Yousef
, p. 70 - 78 (2016/09/02)
(Z)-N-methyl-C-4-substituted phenyl nitrones –O+N(Me)=C(H)R (Z-2a R = 4-ClC6H4, Z-2b R = 4-NO2C6H4, Z-2c R = 4-CH3OC6H4) were synthesized and cha
Synthesis and application of phenyl Nitrone derivatives as acidic and microbial corrosion inhibitors
Chen, Shijun,Zhao, Kang,Chen, Gang
, (2015/06/30)
Nitrone has drawn great attention due to its wide applications as a 1,3-dipole in heterocyclic compounds synthesis and the bioactivities. With the special structure, nitrone can also be used as ligand in inorganic chemistry. Based on the current research,
