16090-10-1Relevant articles and documents
Process for preparing 1-(2-ethyl-butyl)-cyclohexanecarboxylic acid
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Page/Page column 7, (2008/12/06)
The present invention relates to a process for the preparation of 1-(2-ethyl-butyl)- cyclohexanecarboxylic acid which is useful as an intermediate in the preparation of pharmaceutical active compounds, wherein cyclohexanecarboxylic acid alkali metal salt reacts with an alkylating agent in the presence of a secondary amine and (C1-C6) alkyllithium, (C3-C6) cycloalkyllithium or phenyllithium.