1609120-87-7Relevant academic research and scientific papers
Copper-Promoted Thiolation of C(sp2)–H Bonds Using a 2-Amino Alkylbenzimidazole Directing Group
Liu, Shuang-Liang,Li, Xue-Hong,Shi, Tan-Hao,Yang, Guang-Chao,Wang, Hai-Li,Gong, Jun-Fang,Song, Mao-Ping
supporting information, p. 2280 - 2289 (2017/05/01)
A copper-promoted thiolation of C(sp2)–H bonds with disulfides was achieved by using 2-amino alkylbenzimidazole (MBIP amine) as a new and removable N,N-bidentate directing group. This strategy gives a variety of functionalized thioethers in moderate to excellent yields in a simple and efficient way. Importantly, the substrate scope is not limited to aromatic amides; diverse alkenyl amides are also compatible. Furthermore, this synthetic approach provides a potentially feasible way to achieve structural modification of related benzimidazole-containing compounds through direct C–H activation.
Nickel-catalyzed synthesis of diarylsulfides and sulfones via C-H bond functionalization of arylamides
Reddy, Vutukuri Prakash,Qiu, Renhua,Iwasaki, Takanori,Kambe, Nobuaki
, p. 6803 - 6813 (2015/06/25)
The direct sulfenylation and sulfonylation of (sp2)C-H bonds of benzamide derivatives were achieved using a Ni catalyst with the aid of an 8-aminoquinoline moiety as a bidentate directing group. These protocols represent a convenient route for
Nickel-catalyzed directed sulfenylation of sp2 and sp3 C-H bonds
Ye, Xiaohan,Petersen, Jeffrey L.,Shi, Xiaodong
supporting information, p. 7863 - 7866 (2015/05/13)
Directed sulfenylation of both sp2 and sp3 C-H bonds was achieved through nickel catalyzed directed C-S bond formation, giving the desired product in good to excellent yield (up to 90%). Other metal cations, including Cu, Fe, Pd, Rh, Ru and Co, gave almost no reaction under identical conditions, which highlighted the unique reactivity of this Ni system.
Palladium-catalyzed direct thiolation of aryl C-H bonds with disulfides
Iwasaki, Masayuki,Iyanaga, Miki,Tsuchiya, Yuta,Nishimura, Yugo,Li, Wenjuan,Li, Zhiping,Nishihara, Yasushi
supporting information, p. 2459 - 2462 (2014/03/21)
A catalytic variant of the direct thiolation of arenes, bearing directing groups, with disulfides or thiols has been developed under palladium and copper co-catalysis. Both sulfenyl moieties of the disulfide could be incorporated into the thiolated produc
