1609178-44-0

Upstream product

• 67-56-1 methanol 
• 1609178-43-9 (S)-5,5-dimethyl-7-((R,E)-4-phenylbut-3-en-2-yl)-4,6-dioxaspiro[2.5]octane 
• 1609178-42-8 (S)-2-((S)-5,5-dimethyl-4,6-dioxaspiro[2.5]octan-7-yl)propanal 

Downstream Products

• 162465-27-2 (3S,4R,5E)-3-[(tert-butyldimethylsilyl)oxy]-4-methyl-6-phenyl-5-hexenal 
• 1609178-46-2 (2E,5S,6R,7E)-ethyl 5-hydroxy-6-methyl-8-phenylocta-2,7-dienoate 
• 1609178-45-1 (3S,4R,E)-methyl 3-(tert-butyldimethylsilyloxy)-4-methyl-6-phenylhex-5-enoate 

Relevant academic research and scientific papers

A cyclopropanol-based approach to synthesis of Unit A of the cryptophycins

A new asymmetric synthesis of Unit A of the cryptophycins has been carried out yielding 13% of the target product over 14 steps. The key steps of the synthesis were diastereoselective hydroboration-oxidation reactions performed on the alkenyl moiety of a